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浏览/检索结果: 共192条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11 作者:  Zhao, Yitian;  Zhang, Min;  Hou, Xudong;  Han, Jiaxin;  Qin, Xiaoya   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Salicylanilide  hPL inhibitor  Structure -activity relationship  Anti -obesity   Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16 作者:  He, Yulong;  Li, Shunyi;  Zhu, Yueyue;  Wang, Yujie;  Chen, Yuqi   |  收藏  |  浏览/下载：62/0  |  提交时间：2023/10/17 Structure-activity relationship  FABP4 inhibitor  Biphenyl scaffold  Selectivity  Oral bioavailability  Anti-inflammation   Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 246, 页码: 11 作者:  Chen, Lili   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 Phenotypic screening  Gluconeogenesis  Furan-2-carboxylic acid  T2DM   Efficient Detection of Pre-Proinsulin by Double Antibody Sandwich ELISA 期刊论文  OAI收割 APPLIED SCIENCES-BASEL, 2022, 卷号: 12 作者:  Zhu, Zhu;  Wang, Han;  Wang, Li;  Wei, Zhou;  Zheng, Zhiming   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/12/22 recombinant human insulin  pre-proinsulin  monoclonal antibody  sandwich ELISA   Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors 期刊论文  OAI收割 Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1 作者:  Deng,Xu;  Huang,Su-Ling;  Ren,Jian;  Pan,Zheng-Hong;  Shen,Yu   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/11/11 Metabolic syndrome  Tanshinones  Selective 11β-HSD1 inhibitors  Structure–activity relationships   Development and structure-activity relationships of tanshinones as selective 11beta-hydroxysteroid dehydrogenase 1 inhibitors 期刊论文  OAI收割 Natural products and bioprospecting, 2022, 卷号: 12, 期号: 1, 页码: 36 作者:  Deng, Xu;  Huang, Su-Ling;  Ren, Jian;  Pan, Zheng-Hong;  Shen, Yu   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/03/15 Metabolic syndrome  Selective 11beta-HSD1 inhibitors  Structure-activity relationships  Tanshinones   Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14 作者:  Huang, Su-Ling;  Xie, Wei;  Ye, Yang-Liang;  Liu, Jia;  Qu, Hui   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/11/11 type 2 diabetes mellitus  coronarin A  glycogen synthesis  gluconeogenesis  mTORC1  IRS1   Co-activating the AMPK signaling axis by low molecular weight fucoidan LF2 and fucoxanthin improves the HFD-induced metabolic syndrome in mice 期刊论文  OAI收割 JOURNAL OF FUNCTIONAL FOODS, 2022, 卷号: 94, 页码: 9 作者:  Deng, Zhenzhen;  Wang, Jing;  Wu, Ning;  Geng, Lihua;  Zhang, Quanbin   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/08/17 Fucoxanthin  Fucoidan  Metabolic Syndrome  AMPK Signaling Axis   Design, synthesis and structural-activity relationship studies of phanginin A derivatives for regulating SIK1-cAMP/CREB signaling to suppress hepatic gluconeogenesis 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 232, 页码: 14 作者:  Wu, Xing-De;  Huang, Suling;  Shi, Yu;  Shen, Yu;  Tu, Wen-Chao   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/08/16 Hepatic gluconeogenesis  Type 2 diabetes  Phanginin A derivatives  SIK1  Structural-activity relationship   Chemical Constituents of Sinularia nanolobata from the South China Sea 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 42, 期号: 3, 页码: 891-895 作者:  Zeng Zirong;  Zhang Mengmeng;  Wang Hong;  Li Jia;  Guo Yuewei   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/08/16 south china sea: Sinularia nanolobata  prenylelemane-type diterpene  protein tyrosine phosphatase-1B (PTPIB) inhibitory activity