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浏览/检索结果: 共542条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906 作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/04/09 pH-responsive nanogels with enhanced antioxidant and antitumor activities on drug delivery and smart drug release 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 257, 页码: 16 作者:  Ma, Bing;  Li, Qing;  Mi, Yingqi;  Zhang, Jingjing;  Tan, Wenqiang   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 Benzimidazole-chitosan quaternary ammonium  salt  Nanogels  pH-responsive  Antioxidant activity  Antitumor activity   Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/02/19 Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:     |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891 作者:  Jin, Shuhan;  Li, Bo;  Zhang, Bibo;  Gao, Xuejie;  Jia, Xinyan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 dihydrocelastrol  multiple myeloma  JAK2/STAT3  PSMB5  bortezomib resistance   Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5 作者:  Wang, Yujie;  Xu, Keshi;  Liu, Hongchun;  Zhang, Wei;  Hu, Chun   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/19 Auristatin E  beta-Glucuronidase  Antiproliferation  Tumor microenvironment   Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2023, 页码: 10 作者:  Zhou, Rongyao;  Wang, Xiyuan;  Zhang, Deqiang;  Zhan, Zhengsheng;  Duan, Wenhu   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 STING  CDN  Benzo[b]thiophene-2-carboxamide  Cellular activity   Preparation of imidazole acids grafted chitosan with enhanced antioxidant, antibacterial and antitumor activities 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2023, 卷号: 315, 页码: 16 作者:  Ma, Bing;  Zhang, Jingjing;  Mi, Yingqi;  Miao, Qin;  Tan, Wenqiang   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/11/15 Imidazole acids grafted chitosan  Antioxidant activity  Antibacterial activity  Antitumor activity   Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1701-1711 作者:  Zhao, Wen-si;  Chen, Kai-feng;  Liu, Man;  Jia, Xing-long;  Huang, Yu-qi   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 natural products  proteomics  ABPP  eriocalyxin B  parthenolide   Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9 作者:  Li, Hua-ying;  Chen, Yi-li;  Deng, Xiang-nan;  Li, Huan-huan;  Tan, Jie   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 cancer immunotherapy  B7-H3  PD-L1  bispecific antibodies  VHH  antibody-dependent cell-mediated cytotoxicity (ADCC)