机构

• 上海药物研究所 [18]
• 化学研究所 [2]
• 大连化学物理研究所 [1]
• 昆明植物研究所 [1]
• 上海生物化学与细胞生... [1]

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [23]

发表日期

• 2023 [2]
• 2022 [3]
• 2021 [2]
• 2020 [5]
• 2018 [9]
• 2016 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 GPCR activation and GRK2 assembly by a biased intracellular agonist 期刊论文  OAI收割 NATURE, 2023, 页码: 27 作者:  Duan, Jia;  Liu, Heng;  Zhao, Fenghui;  Yuan, Qingning;  Ji, Yujie   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Conserved class B GPCR activation by a biased intracellular agonist 期刊论文  OAI收割 NATURE, 2023, 页码: 25 作者:  Zhao, Li-Hua;  He, Qian;  Yuan, Qingning;  Gu, Yimin;  He, Xinheng   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Molecular recognition of morphine and fentanyl by the human mu-opioid receptor 期刊论文  OAI收割 CELL, 2022, 卷号: 185, 期号: 23, 页码: 4361-+ 作者:  Zhuang, Youwen;  Wang, Yue;  He, Bingqing;  He, Xinheng;  Zhou, X. Edward   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 Effects of site-directed mutagenesis of GLP-1 and glucagon receptors on signal transduction activated by dual and triple agonists 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13 作者:  Darbalaei, Sanaz;  Chang, Ru-lue;  Zhou, Qing-tong;  Chen, Yan;  Dai, An-tao   |  收藏  |  浏览/下载：20/0  |  提交时间：2022/09/30 glucagon-like peptide-1 receptor  glucagon receptor  dual and triple agonist  cAMP  pERK1/2  unimolecular polypharmacology   Recent progress in assays for GPCR drug discovery 期刊论文  OAI收割 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022, 卷号: 323, 期号: 2, 页码: C583-C594 作者:  Guo, Shimeng;  Zhao, Tingting;  Yun, Ying;  Xie, Xin   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/04/10 biased signaling  GPCR  high -throughput screening assays  humanized mouse model  protein  protein interaction   Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2021, 页码: 24 作者:  Shao, Zhehua;  Shen, Qingya;  Yao, Bingpeng;  Mao, Chunyou;  Chen, Li-Nan   |  收藏  |  浏览/下载：22/0  |  提交时间：2022/06/15 Discovery of potentially biased agonists of mu-opioid receptor (MOR) through molecular docking, pharmacophore modeling, and MD simulation 期刊论文  OAI收割 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2021, 卷号: 90, 页码: 107405 作者:  Jiang,Xuan;  Li,Shuxiang;  Zhang,Hongbin;  Wang,Liang-Liang   |  收藏  |  浏览/下载：13/0  |  提交时间：2022/04/02 mu-Opioid receptors (MOR)  Biased ligands  Molecular docking  Hip-hop pharmacophore  MD simulation   Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16 作者:  Darbalaei, Sanaz;  Yuliantie, Elita;  Dai, Antao;  Chang, Rulue;  Zhao, Peishen   |  收藏  |  浏览/下载：19/0  |  提交时间：2020/12/21 G protein-coupled receptor  Glucagon-like peptide-1 receptor  Glucagon receptor  Biased agonism  Unimolecular dual agonist   Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13 作者:  Yuliantie, Elita;  Darbalaei, Sanaz;  Dai, Antao;  Zhao, Peishen;  Yang, Dehua   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/12/24 G protein-coupled receptor  Glucose-dependent insulinotropic peptide receptor  Glucagon-like peptide-1 receptor  Biased agonist  GPCR signaling   SAMPL6 host-guest binding affinities and binding poses from spherical-coordinates-biased simulations 期刊论文  OAI收割 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2020, 卷号: 34, 期号: 5, 页码: 589-600 作者:  Sun, Zhaoxi;  He, Qiaole;  Li, Xiao;  Zhu, Zhengdan   |  收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 Free energy calculation  Binding pose  Binding affinity  Spherical coordinates  SAMPL6