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• 上海药物研究所 [18]
• 上海生物化学与细胞... [16]
• 昆明动物研究所 [11]
• 上海营养与健康研究所 [7]
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• OAI收割 [73]
• iSwitch采集 [3]

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• 期刊论文 [72]
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• 2023 [3]
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• 2021 [4]
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学科主题

• Biochemist... [6]
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浏览/检索结果: 共76条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Uncovering the role of FOXA2 in the Development of Human Serotonin Neurons 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 页码: 15 作者:  Xu, Ting;  Cao, Lining;  Duan, Jinjin;  Li, Yingqi;  Li, You   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 FOXA2  human pluripotent stem cells  RA signaling  serotonin neurons  SHH signaling   Structure-based discovery of potent USP28 inhibitors derived from Vismodegib 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15 作者:  Zhou, Di;  Xu, Zhuo;  Huang, Yaodong;  Wang, Hui;  Zhu, Xiaoli   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 USP28  Structure-based  Vismodegib derivatives  Structure-activity relationships  c-Myc   Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612 作者:  Wang, Xiaomin;  Xu, Jun;  Sun, Yiming;  Cao, Siyuwei;  Zeng, Hanlin   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 HDAC inhibitors  Drug resistance  Histone methylation  Histone acetylation  Epigenetic interplay  Hedgehog pathway  ZIC1  LIFR  Combination therapy  Breast cancer   Inhibition of the transcription factor ZNF281 by SUFU to suppress tumor cell migration 期刊论文  OAI收割 CELL DEATH AND DIFFERENTIATION, 2022, 页码: 14 作者:  Deng, Yanran;  Peng, Dezhen;  Xiao, Jing;  Zhao, Yunhe;  Ding, Wenhao   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/11/11 Solubilization, purification, and ligand binding characterization of G protein-coupled receptor SMO in native membrane bilayer using styrene maleic acid copolymer 期刊论文  OAI收割 PEERJ, 2022, 卷号: 10 作者:  Zhu, Lina;  Zhao, Hongxin;  Wang, Yizhuo;  Yu, Chuandi;  Liu, Juanjuan   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/12/23 GPCR  Dissociation constant  Detergents  Styrene maleic acid copolymer nanodiscs  Smoothened receptors  NMR   The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone 期刊论文  OAI收割 THERANOSTICS, 2022, 卷号: 12, 期号: 17, 页码: 7476-7490 作者:  Zhang, Shaoqing;  Chen, Yue;  Xu, Zhongli;  Yang, Jun;  Sun, Renhong   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/04/10 Hedgehog  Bcl-xL  PROTAC  drug resistance  bone growth   PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation 期刊论文  OAI收割 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10 作者:  Yang, Jun;  Wang, Juan;  Liu, Yuan;  Zhang, Yu;  Huang, Wenjing   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/08/17 Dual activation of Hedgehog and Wnt/beta-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer 期刊论文  OAI收割 AGING-US, 2021, 卷号: 13, 期号: 7, 页码: 10749-10769 作者:  Peng, Yin;  Zhang, Xiaojing;  Lin, Huijuan;  Deng, Shiqi;  Qin, Ying   |  收藏  |  浏览/下载：27/0  |  提交时间：2021/12/01 miRNA-150  SUFU  Wnt/beta-catenin  hedgehog  EMT   Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504 作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian   |  收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24 Medulloblastoma  Hedgehog signaling  pathway  Drug resistance  GLI  BRD4   The hedgehog pathway suppresses neuropathogenesis in CD4 T cell-driven inflammation 期刊论文  OAI收割 BRAIN, 2021, 卷号: 144 作者:  Benallegue, Nail;  Kebir, Hania;  Kapoor, Richa;  Crockett, Alexis;  Li, Cen   |  收藏  |  浏览/下载：23/0  |  提交时间：2021/11/18 sonic hedgehog  neuroinflammation  autoimmunity  experimental autoimmune encephalomyelitis  T cells