中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-35
作者:
Jingru Li
;
Yicheng Chen
;
Jiali Wan
;
Xin Liu
;
Chunrong Yu
  |  
收藏
  |  
浏览/下载:226/0
  |  
提交时间:2017/07/24
Abt-263
Sorafenib
Combination Therapy
Cancer
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 卷号: 72, 期号: 8, 页码: 4142-4154
作者:
Yang, Yu-Hong
;
Chen, Chen
;
Zheng, Yan
;
Wu, Zi-Jian
;
Zhou, Meng-Qing
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/07
fucoxanthin
colitis
intestinal barrier function
anti-inflammation
antioxidation
gut microbiota
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/09
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Comparative chromatin dynamics reveal differential thermal tolerance mechanisms between two congeneric oyster species
期刊论文
OAI收割
AQUACULTURE, 2024, 卷号: 579, 页码: 16
作者:
Wang, Chaogang
;
Jiang, Zhuxiang
;
Du, Mingyang
;
Li, Qingyuan
;
Cong, Rihao
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/04/07
Crassostrea gigas
Crassostrea angulata
ATAC-seq
RNA-Seq
Thermal tolerance
A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Intrinsic and extrinsic pathways of apoptosis induced by multiple antibiotics residues and ocean acidification in hemocytes of scallop Argopecten irradians irradians: An interactionist perspective
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2024, 卷号: 269, 页码: 12
作者:
Zhang, Tianyu
;
Wang, Xin
;
Zhang, Qianqian
;
Li, Ke
;
Yang, Dinglong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/23
Antibiotics residues
Ocean acidification
Apoptosis
Bay scallop
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors