中国科学院机构知识库网格系统: 检索

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	From bench to bedside: current development and emerging trend of KRAS-targeted therapy 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18 作者: Chen, Yi; Liu, Qiu-pei; Xie, Hua; Ding, Jian \| 收藏 \| 浏览/下载：28/0 \| 提交时间：2024/01/16 KRAS mutation KRAS(G12C) inhibitor Pan-KRAS inhibitor SHP2 allosteric inhibitor SOS1 inhibitor combination therapy
	Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead 期刊论文 OAI收割 GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414 作者: Li, Hui-yu; Qi, Wei-liang; Wang, Yu-xiang; Meng, Ling-hua \| 收藏 \| 浏览/下载：117/0 \| 提交时间：2023/10/17 Biomarkers Covalent KRasG12Cinhibitors Drug resistance Human cancers KRASG12Cmutation
	Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors 期刊论文 OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190 作者: Liu, Meiying \| 收藏 \| 浏览/下载：7/0 \| 提交时间：2024/03/27 KRAS mutation SOS1-KRAS interaction SOS1 inhibitor combination therapy
	Safety and Efficacy of D-1553 in Patients with KRAS G12C Mutated Non-Small Cell Lung Cancer: A Phase 1 Trial 期刊论文 OAI收割 JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17 作者: Lu, S.; Jian, H.; Zhang, Y.; Song, Z.; Zhao, Y. \| 收藏 \| 浏览/下载：22/0 \| 提交时间：2022/12/23 Non-small cell lung cancer KRAS G12C mutation Small molecular inhibitor
	Dual inhibition of CDK4 and FYN leads to selective cell death in KRAS-mutant colorectal cancer 期刊论文 OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2019, 卷号: 4 - \| 收藏 \| 浏览/下载：8/0 \| 提交时间：2020/10/26