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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共235条，第1-10条 帮助

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Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke
  |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Zhang, Ying;  Wu, Jianbo
  |  收藏  |  浏览/下载：5/0  |  提交时间：2024/01/26
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu
  |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26
Oral Delivery of Gemcitabine-Loaded Glycocholic Acid-Modified Micelles for Cancer Therapy 期刊论文  OAI收割
ACS NANO, 2023, 卷号: 17, 期号: 18, 页码: 18074-18088
作者:  Zang, Wenqing;  Gao, Duo;  Yu, Miaorong;  Long, Manmei;  Zhang, Zhuan
  |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303
作者:  Xiang, Weiguo;  Zhao, Lijie;  Han, Xin;  Xu, Tianfeng;  Kregel, Steven
  |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08
Src is a target molecule of mannose against pancreatic cancer cells growth in vitro & amp; in vivo 期刊论文  OAI收割
GLYCOBIOLOGY, 2023, 页码: 18
作者:  Xie, Jianhao;  Wu, Shengjie;  Liao, Wenfeng;  Ning, Jingru;  Ding, Kan
  |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17
Enhancing the oral bioavailability of poorly water-soluble amisupiride with solid nanodispersion 期刊论文  OAI收割
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2023, 卷号: 86, 页码: 6
作者:  Zhang, Xinyue;  Li, Jie;  Rong, Rong;  Wang, Dangge;  Wang, Donghai
  |  收藏  |  浏览/下载：65/0  |  提交时间：2023/10/17
Combining gut microbiota modulation and chemotherapy by capecitabine-loaded prebiotic nanoparticle improves colorectal cancer therapy 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 16
作者:  Lang, Tianqun;  Zhu, Runqi;  Zhu, Xiao;  Yan, Wenlu;  Li, Yu
  |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:  Li, Daqiang;  Zhang, Zhuo;  Li, Yalei;  Wang, Xinyi;  Zhong, Hanyue
  |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17
Design, Synthesis, and Evaluation of (R)-8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3-d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17
作者:  Li, Qian;  Zhang, Tao;  Song, Peiran;  Tong, Linjiang;  Feng, Fang
  |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17