中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [111]
上海神经科学研究所 [23]
西北高原生物研究所 [20]
上海生物化学与细胞... [18]
昆明动物研究所 [11]
大连化学物理研究所 [7]
更多
采集方式
OAI收割 [273]
iSwitch采集 [7]
内容类型
期刊论文 [268]
学位论文 [10]
专利 [1]
会议论文 [1]
发表日期
2022 [5]
2021 [4]
2020 [9]
2019 [11]
2018 [13]
2017 [10]
更多
学科主题
Biochemis... [19]
Neuroscie... [10]
Pharmacolo... [8]
Biophysics [5]
Toxicology [5]
Biochemist... [4]
更多
筛选
浏览/检索结果:
共280条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG
期刊论文
OAI收割
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14
作者:
Liu, Zhipei
;
Wang, Feng
;
Yuan, Hui
;
Tian, Fuyun
;
Yang, Chuanyan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
hERG
K525N
Gating Polarity
Voltage-Sensing Domain
LQT2
Ligand activation mechanisms of human KCNQ2 channel
期刊论文
OAI收割
Nature communications, 2023, 卷号: 14, 期号: 1, 页码: 6632
作者:
Ma, Demin
;
Zheng, Yueming
;
Li, Xiaoxiao
;
Zhou, Xiaoyu
;
Yang, Zhenni
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/26
Identification and characterization of the key lethal toxin from jellyfish Cyanea nozakii
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 230, 页码: 8
作者:
Li, Rongfeng
;
Yu, Huahua
;
Li, Aoyu
;
Yu, Chunlin
;
Li, Pengcheng
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/13
Jellyfish
Venom
Toxin
Letoxcn
Cyanea nozakii
Epilepsy phenotype and response to KCNQ openers in mice harboring the Kcnq2 R207W voltage-sensor mutation
期刊论文
OAI收割
NEUROBIOLOGY OF DISEASE, 2022, 卷号: 174, 页码: 10
作者:
Tian, Fuyun
;
Cao, Birong
;
Xu, Haiyan
;
Zhan, Li
;
Nan, Fajun
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/13
KCNQ2
Epilepsy
Mouse model
HN37 (pynegabine)
Diversity-oriented synthesis of marine polybrominated diphenyl ethers as potential KCNQ potassium channel activators
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 126, 页码: 105909
作者:
Liu, Lai-Xin
;
Gu, Ru-Rong
;
Jin, Yang
;
Chen, Xue-Qin
;
Li, Xu-Wen
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/21
Marine Natural product
Polybrominated diphenyl ethers
KCNQ potassium channel
General Pharmacological Activation Mechanism of K+ Channels Bypassing Channel Gates
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:
Liu, Shijie
;
Guo, Peipei
;
Wang, Kun
;
Zhang, Shaoying
;
Li, Ya
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/08/30
Transcriptomic and Proteomic Analysis of Marine Nematode Litoditis marina Acclimated to Different Salinities
期刊论文
OAI收割
GENES, 2022, 卷号: 13, 期号: 4, 页码: 24
作者:
Xie, Yusu
;
Zhang, Liusuo
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/07/18
salinity
euryhalinity
hyposaline
hypersaline
marine nematode
Litoditis marina
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:
Li, Xiaokang
;
Li, Jinwen
;
Huang, Yunyuan
;
Gong, Qi
;
Fu, Yan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/15
Alzheimer's disease
Depression
Comorbidity
Multi-target-directed ligands
New Insights Into Potassic Intraplate Volcanism in Northeast China From Joint Tomography of Ambient Noise and Teleseismic Surface Waves
期刊论文
OAI收割
JOURNAL OF GEOPHYSICAL RESEARCH-SOLID EARTH, 2021, 卷号: 126, 期号: 8, 页码: 17
作者:
Chen, Ying
;
Ai, Yinshuang
;
Jiang, Mingming
;
Yang, Yingjie
;
Lei, Jianshe
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/01
3-D S-wave velocity model
Potassic Intraplate Volcanism
Northeast China
Ambient noise tomography
Two-plane surface wave tomography