中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [144]
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2023 [47]
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Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
Target aided self-assembly of DNA hyperbranched nanostructures for bacterial 16 S ribosomal DNA gene SERS detection
期刊论文
OAI收割
SENSORS AND ACTUATORS B-CHEMICAL, 2023, 卷号: 396, 页码: 7
作者:
Zeng, Yan
;
Qi, Peng
;
Chen, Jiawei
;
Wang, Peng
;
Zhang, Dun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/11/30
DNA hyperbranched nanostructure
SERS
Target aided
Bacterial 16 S rDNA genes
MiR-337-3p improves metabolic-associated fatty liver disease through regulation of metabolism
期刊论文
OAI收割
ISCIENCE, 2023, 卷号: 26, 期号: 11, 页码: 18
作者:
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
SGF29 nuclear condensates reinforce cellular aging
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 21
作者:
Yan, Kaowen
;
Ji, Qianzhao
;
Zhao, Dongxin
;
Li, Mingheng
;
Sun, Xiaoyan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/11
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
;
Nie, Shenyou
;
Zhao, Jidong
;
Yao, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics
Deciphering the neural mechanisms of miR-134 in major depressive disorder with population-based and person-specific imaging transcriptomic techniques
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2023, 卷号: 329, 页码: 12
作者:
Lou, Jing
;
Liu, Kai
;
Wen, Junyan
;
He, Yini
;
Sun, Yuqing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/22
Major depressive disorder (MDD)
miR-134
Two -stage cross -scale imaging transcriptomic
analyses
Biomarkers
Multi-omics
Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein
期刊论文
OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 9
作者:
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate:
In
silico
toxicogenomic data-mining,
in
vivo,
and toxicity pathway-oriented approach
期刊论文
OAI收割
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
作者:
Wang, Xiaoqing
;
Li, Fei
;
Meng, Xiangjing
;
Xia, Chunlei
;
Ji, Chenglong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/15
Plastic additives
Graphene-based nanomaterials
Toxicogenomic data mining
Combined hazards
Developmental abnormality
Integrated analysis of a miRNA-mRNA network related to immunity and autophagy in Macrobrachium rosenbergii infected with Aeromonas hydrophila
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 141, 页码: 11
作者:
Wang, Feifei
;
Zhao, Fei
;
Tan, Aiping
;
Deng, Yuting
;
Wang, Ling
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/30
Macrobrachium rosenbergii
miRNA-mRNA
Immunity
Autophagy
Aeromonas hydrophila