中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [343]
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Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Recognition of methamphetamine and other amines by trace amine receptor TAAR1
期刊论文
OAI收割
NATURE, 2023, 卷号: 624, 期号: 7992, 页码: 663-+
作者:
Liu, Heng
;
Zheng, You
;
Wang, Yue
;
Wang, Yumeng
;
He, Xinheng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/25
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
;
Nie, Shenyou
;
Zhao, Jidong
;
Yao, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics
A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-naïve first episode schizophrenia: pharmacogenetic impact of cyclooxygenase-2 functional polymorphisms
期刊论文
OAI收割
NEUROPSYCHOPHARMACOLOGY, 2023, 页码: 10
作者:
Wang, Dong-Mei
;
Chen, Da-Chun
;
Xiu, Mei-Hong
;
Wang, Li
;
Kosten, Thomas R.
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/06
'Passive' nanoparticles for organ-selective systemic delivery: design, mechanism and perspective
期刊论文
OAI收割
CHEMICAL SOCIETY REVIEWS, 2023
作者:
Fu, Liyi
;
Zhang, Yang
;
Farokhzad, Ryan A.
;
Mendes, Barbara B.
;
Conde, Joao
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/17
Oncopia Therapeutics Inc., Proteovant Therapeutics Inc.
项目
OAI收割
资助机构: Oncopia Therapeutics Inc., Proteovant Therapeutics Inc., 2023-
-
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/12/08
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303
作者:
Xiang, Weiguo
;
Zhao, Lijie
;
Han, Xin
;
Xu, Tianfeng
;
Kregel, Steven
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Multi-omics for COVID-19: driving development of therapeutics and vaccines
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 9, 页码: 30
作者:
Guo, Mengyu
;
Xiong, Muya
;
Peng, Jinying
;
Guan, Tong
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/19
COVID-19
SARS-CoV-2
multi-omics
antibodies
small-molecule drugs
vaccines
Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18
作者:
Lu, Lixue
;
Chen, Song
;
Yu, Mingcheng
;
Zhou, Ronghui
;
Guo, Siqi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
ROR gamma t
Triazines
Inverse agonist
Psoriasis
Autoimmune diseases