中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Steric repulsion introduced by loop constraints modulates the microphase separation of chromatins
期刊论文
OAI收割
JOURNAL OF CHEMICAL PHYSICS, 2024, 卷号: 160, 期号: 5, 页码: 9
作者:
Wei, Jiachen
;
Xue, Yue
;
Liu, Yawei
;
Tian, Hao
;
Shao, Yingfeng
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/11
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
Machine learning and experimental screening of chromatin regulator signatures and potential drugs in hepatitis B related hepatocellular carcinoma
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 15
作者:
Jia, Caixia
;
Chen, Jianxin
;
Wang, Xueting
;
Yang, Xingliang
;
Wu, Hongxing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/18
Chromatin regulators
hepatitis B related HCC
immune
HepG2.2.15
potential drugs
resveratrol
HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 17
作者:
Li, Jialun
;
Lu, Lu
;
Liu, Lingling
;
Ren, Xuelian
;
Chen, Jiwei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/10/17
ARID3a from the ARID family: structure, role in autoimmune diseases and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Guo, Cheng-cen
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
transcription factors
ARID
ARID3a
autoimmune diseases
systemic lupus erythematosus
primary biliary cholangitis
Reorganization of three-dimensional chromatin architecture in Medicago truncatula under phosphorus deficiency
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL BOTANY, 2023, 卷号: 74, 期号: 6, 页码: 2005-2015
作者:
Wang, Tianzuo
;
Wang, Jing
;
Chen, Li
;
Yao, Jiaying
;
Yuan, Zan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/07
3D chromatin architecture
histone modification
hormonal response
Medicago truncatula
phosphorus deficiency
root system architecture
transcriptional regulation
Discovery of CECR2 Bromodomain Inhibitors with High Selectivities over BPTF Bromodomain
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 2072-2080
作者:
Lu, Haibo
;
Zu, Shijia
;
Duan, Zhe
;
Feng, Yueyao
;
Wang, Jie
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
CECR2 bromodomain
BPTF bromodomain
Inhibitors
Structure-activity relationships
chemical probe
Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12
作者:
Ding, Hong
;
Pei, Yuan
;
Li, Yuanqing
;
Xu, Wen
;
Mei, Lianghe
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
Epigenetics
Histone acetyltransferase
P300/CBP
Ovarian cancer
Terpyridine Zn(II) Complexes with Azide Units for Visualization of Histone Deacetylation in Living Cells under STED Nanoscopy
期刊论文
OAI收割
ACS SENSORS, 2021, 卷号: 6
作者:
Du, Wei
;
Pan, Dayi
;
Xiang, Pan
;
Xiong, Chaoya
;
Zhang, Mingzhu
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/03/21
Zn complexes
azide units
histone probe
STED nanoscopy
super-resolution imaging
Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5
期刊论文
OAI收割
MOLECULES, 2021, 卷号: 26, 期号: 5, 页码: 12
作者:
Cao, Jiawen
;
Fan, Tiantian
;
Li, Yanlian
;
Du, Zhiyan
;
Chen, Lin
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2021/05/24
phage display
biopanning
WDR5
cocrystal structure