中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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福建物质结构研究所 [43]
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Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Near-Neighbor Electron Orbital Coupling Effect of Single-Atomic-Layer Au Cluster Intercalated Bilayer 2H-TaS
2
for Surface Enhanced Raman Scattering Sensing
期刊论文
OAI收割
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2023, 卷号: 14
作者:
Weng, Shirui
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/10
Photophysical Exploration of Alectinib and Rilpivirine: Insights from Theory and Experiment
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 16, 页码: 16
作者:
Zhang, Chun
;
Yang, Yuting
;
Gan, Suya
;
Ren, Aimin
;
Zhou, Yu-Bo
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
fluorescence imaging
Alectinib
Rilpivirine
quantum chemistry
Laeviganoids A-T, ent-Clerodane-Type Diterpenoids from Croton laevigatus
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2023, 页码: 15
作者:
Wang, Cheng-Lei
;
Dai, Yang
;
Zhu, Qiong
;
Peng, Xia
;
Liu, Quan-Fang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20
作者:
Chen, Yuting
;
Shi, Qiongyu
;
Yang, Hong
;
Li, Jiayi
;
Zhou, Kaixin
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Epigenetic
PRMT5 inhibitor
Nucleoside derivatives
Structure-activity Relationship Prodrug
Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 22, 页码: 15374-15390
作者:
Chan, Shingpan
;
Zhang, Yunong
;
Wang, Jie
;
Yu, Qiuchun
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 241, 页码: 16
作者:
Shen, Ancheng
;
Li, Xiyuan
;
Zhang, Yan
;
Ma, Jing
;
Xiao, Ruoxuan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
Innate immunity
STING Agonists
Structural modification
Immuno-oncology
Discovery of Novel Imidazo[4,5-c]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Intestinal Homeostasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21
作者:
Liang, Xuewu
;
Xie, Yongle
;
Liu, Xuyi
;
Xu, Hui
;
Ren, Hairu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/11/11
Molecular characteristics, sources and environmental risk of aromatic compounds in particulate matter during COVID-2019: Nontarget screening by ultra-high resolution mass spectrometry and comprehensive two-dimensional gas chromatography
期刊论文
OAI收割
ENVIRONMENT INTERNATIONAL, 2022, 卷号: 167, 期号: 0, 页码: 107421
作者:
Xu, Chi
;
Gao, Lirong
;
Lyu, Yibing
;
Qiao, Lin
;
Huang, Di
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/11/08
HYDROCARBONS PAHS
ORGANIC-COMPOUNDS
APEC SUMMIT
POLLUTION
EMISSION
PM2.5
AEROSOLS
SUBSTANCES
HAZE
In Situ Genomics and Transcriptomics of SAR202 Subclusters Revealed Subtle Distinct Activities in Deep-Sea Water
期刊论文
OAI收割
MICROORGANISMS, 2022, 卷号: 10, 期号: 8, 页码: 16
作者:
Wei, Zhanfei
;
Li, Qingmei
;
Lu, Rui
;
Zheng, Pengfei
;
Wang, Yong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2022/10/09
microbial community
SAR202
DOM
omics data
MISNAC