机构

• 上海药物研究所 [61]
• 西北高原生物研究所 [34]
• 大连化学物理研究所 [26]
• 昆明植物研究所 [9]
• 生态环境研究中心 [8]
• 合肥物质科学研究院 [8]
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采集方式

• OAI收割 [187]
• iSwitch采集 [4]

内容类型

• 期刊论文 [186]
• 学位论文 [3]
• 会议论文 [2]

发表日期

• 2023 [9]
• 2022 [5]
• 2021 [9]
• 2020 [3]
• 2019 [12]
• 2018 [17]
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学科主题

• 物理化学 [6]
• Biophysics [2]
• Biochemist... [1]
• Cell Biolo... [1]
• Chemistry,... [1]
• 生物科学 [1]
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筛选

浏览/检索结果: 共191条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches 期刊论文  OAI收割 BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17 作者:  Sultan, Rida;  Ahmed, Abrar;  Wei, Li;  Saeed, Hamid;  Islam, Muhammad   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/19 CDK2  ER+ Breast cancer  Molecular Docking  MM-GBSA  Molecular Dynamic Simulations  MTT assay  Moringa oleifera  Phytoconstituents  Chlorogenic acid   Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15 作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 N-cyclopropylmethyl nornepenthone derivatives  derivatives  Structure-activity relationship  MOR antagonist  Functional reversal  Reversal of subtype-selectivity  Opioid use disorder   Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPAR alpha agonists by in silico studies and biochemical evaluation 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 16 作者:  Li, Yue;  Lv, Mengjia;  Shen, Meiling;  Gu, Xi;  Zhang, Li   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 NAFLD  PPAR alpha agonist  virtual screening  biochemical evaluation   Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11 作者:  Zhao, Yitian;  Zhang, Min;  Hou, Xudong;  Han, Jiaxin;  Qin, Xiaoya   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Salicylanilide  hPL inhibitor  Structure -activity relationship  Anti -obesity   MEDIATE-Molecular DockIng at homE: Turning collaborative simulations into therapeutic solutions 期刊论文  OAI收割 EXPERT OPINION ON DRUG DISCOVERY, 2023, 页码: 13 作者:  Vistoli, Giulio;  Manelfi, Candida;  Talarico, Carmine;  Fava, Anna;  Warshel, Arieh   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 Collaborative computing  virtual screening  docking simulations  drug repurposing  SARS-CoV-2  artificial intelligence   Identification of lignans as ATP citrate lyase (ACLY) inhibitors from the roots of Pouzolzia zeylanica 期刊论文  OAI收割 NATURAL PRODUCT RESEARCH, 2023, 页码: 8 作者:  Li, Jin-Long;  Jiang, Jia-Yi;  Gu, Shan-Shan;  Zhang, Lei;  Sun, Yan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Pouzolzia zeylanica  lignans  ATP citrate lyase (ACLY) inhibitors   Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 226, 页码: 780-792 作者:  Xiang, Yusen;  Zhai, Guanglei;  Li, Yaozong;  Wang, Mengge;  Chen, Xixiang   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/04/10 SARS-CoV-2  S-RBD  Ginkgolic acid   Fructose-1,6-bisphosphatase 1 dephosphorylates I kappa B alpha and suppresses colorectal tumorigenesis 期刊论文  OAI收割 CELL RESEARCH, 2023, 页码: 13 作者:  Zhu, Wencheng;  Chu, Huiying;  Zhang, Yajuan;  Luo, Tianhang;  Yu, Hua   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/04/10 Unraveling the Therapeutic Mechanism of Saussurea involucrata against Rheumatoid Arthritis: A Network Pharmacology and Molecular Modeling-Based Investigation 期刊论文  OAI收割 NUTRIENTS, 2023, 卷号: 15, 期号: 19 作者:  Chen, Jinghua;  Wu, Xiaoke;  Yu, Ruitao   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/01 Cyclopiumolides A and B, unusual 13-membered macrolides from the deep sea-sourced fungus Penicillium cyclopium SD-413 with antiproliferative activities 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7 作者:  Li, Yan-He;  Yang, Sui-Qun;  Li, Xiao-Ming;  Li, Xin;  Wang, Bin-Gui   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/01/06 Macrolides  Penicillium cyclopium  Deep-sea sediment  Cytotoxicity