中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [126]
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A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14
作者:
Yang, Li
;
Gong, Ying
;
Liu, Feifei
;
Chen, Wuhong
;
Wang, Xinran
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/19
Hepatitis B virus
Capsid assembly
Phthalazinone derivatives
Apoptosis
Machine learning and experimental screening of chromatin regulator signatures and potential drugs in hepatitis B related hepatocellular carcinoma
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 15
作者:
Jia, Caixia
;
Chen, Jianxin
;
Wang, Xueting
;
Yang, Xingliang
;
Wu, Hongxing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/18
Chromatin regulators
hepatitis B related HCC
immune
HepG2.2.15
potential drugs
resveratrol
TPN10475 alleviates concanavalin A-induced autoimmune hepatitis by limiting T cell development and function through inhibition of PI3K-AKT pathway
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 13
作者:
Wang, Chun
;
Han, Mengyao
;
Li, Xinhang
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/01/16
AIH
T cell
Pro-inflammatory
IFN-gamma
PI3K-AKT
Advances in biosynthesis of peptide drugs: Technology and industrialization
期刊论文
OAI收割
BIOTECHNOLOGY JOURNAL, 2023, 页码: 13
作者:
Wang, Jing
;
Chen, Long
;
Qin, Song
;
Xie, Mingyuan
;
Luo, Shi-Zhong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/26
biosynthesis technology
industrialization
peptide drugs
peptide synthesis
A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8
作者:
Chen, Wuhong
;
Gong, Ying
;
Long, Guozhang
;
Wang, Xinran
;
Yang, Yurong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
HBV
Capsid assembly modulators
Prodrug
Hepatitis B surface antigen
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Potential roles of IFI44 genes in high resistance to Vibrio in hybrids of Argopecten scallops
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 135, 页码: 9
作者:
Qu, Xiaoxu
;
Wang, Xia
;
Liu, Bo
;
Chen, Min
;
Ning, Junhao
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收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/15
Argopecten scallops
Hybrids
Resistance
Heterosis
IFI44
Vibrio anguillarum
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma
期刊论文
OAI收割
NATURE METABOLISM, 2023, 页码: 35
作者:
Yang, Zijian
;
Yan, Cong
;
Ma, Jiaqiang
;
Peng, Panpan
;
Ren, Xuelian
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
Combined Use of Immune Checkpoint Inhibitors and Phytochemicals as a Novel Therapeutic Strategy against Cancer
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 12, 页码: 2315-2328
作者:
Luo, LingJie
;
Lin, Caiji
;
Wang, Pengfei
;
Cao, Danli
;
Lin, Yiru
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Immune checkpoint inhibitor
Phytochemicals
Combination therapy
Immune-related adverse events
Predictive biomarker
Gut microbiota
Hepatoprotective Mechanism and Material Basis of Swertia Plants Based On Network Pharmacology and Molecular Docking Method
期刊论文
OAI收割
LATIN AMERICAN JOURNAL OF PHARMACY, 2023, 卷号: 42, 期号: 2, 页码: 374
作者:
Huang, Xian-Ju
;
Liu, Shi-Quan
;
Dai, Jia-Wei
;
LI, Tian-Cai
;
Wu, Zhou-Yang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/01