中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [115]
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Discovery of GPX4 inhibitors through FP-based high-throughput screening
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Cao, Yu
;
Wu, Bin
;
Xu, Ying
;
Wang, Mingchen
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/02/27
GPX4 inhibitor
HTS assay
Ferroptosis
Fluorescence polarization
Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF)
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:
Wu, Xinyu
;
Wang, Mingchen
;
Cao, Yu
;
Xu, Ying
;
Yang, Ziqun
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/02/27
O-GlcNAcylation
O-GlcNAc transferase
High-throughput screening
Inhibitor
An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 84, 页码: 117262
作者:
Xie, Yanqiu
;
Fan, Shijie
;
Ni, Dongxuan
;
Wan, Wei
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
ATG4B inhibitor
DC-ATG4in
Sorafenib
Hepatocellular Carcinoma
Combination therapy
Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 650, 页码: 117-122
作者:
Ni, Yicheng
;
Luo, Zhongyuan
;
Lv, Yixin
;
Ma, Shuyuan
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Thioredoxin reductase 1 inhibitor
Chemical probe
High -throughput screening
Thimerosal
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors
期刊论文
OAI收割
PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27
作者:
Zang, Yi
;
Su, Mingbo
;
Wang, Qingxing
;
Cheng, Xi
;
Zhang, Wenru
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
high-throughput screening
SARS
CoV-2
main
papain-like
proteases
Simulating androgen receptor selection in designer yeast
期刊论文
OAI收割
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
(-)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8
作者:
Liu, Tonghai
;
Shi, Wenjia
;
Ding, Yiluan
;
Wu, Qiqi
;
Zhang, Bei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/13
NAD kinase inhibitor
(-)-epigallocatechin gallate
hydrogen-deuterium exchange mass spectrometry
KRAS
The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 73, 页码: 6
作者:
Wu, Qiqi
;
Sun, Zhongya
;
Chen, Zhifeng
;
Liu, Jingqiu
;
Ding, Hong
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/08/30
Glutamate oxaloacetate transaminase 1
Inhibitor
Hydralazine hydrochloride
High -throughput screening
Phosphodiesters as GPR84 Antagonists for the Treatment of Ulcerative Colitis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3991-4006
作者:
Chen, Lin-Hai
;
Zhang, Qing
;
Xiao, Yu-Feng
;
Fang, You-Chen
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14
作者:
Xiao, Senhao
;
Guo, Siqi
;
Han, Jie
;
Sun, Yanli
;
Wang, Mingchen
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/15