中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [212]
上海生物化学与细胞... [20]
大连化学物理研究所 [14]
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期刊论文 [327]
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浏览/检索结果:
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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Discovery of novel isopropanolamine inhibitors against MoTPS1 as potential fungicides with unique mechanisms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 260, 页码: 14
作者:
Jiang, Zhiyang
;
Shi, Dongmei
;
Chen, Yitong
;
Li, Huilin
;
Wang, Jin 'e
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Rice blast
Trehalose-6-phosphate synthase
Isopropanolamine compounds
Inhibitor
Fungicidal mechanism
Development of a novel
18
F-labeled small molecule probe for PET imaging of mesenchymal epithelial transition receptor expression
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 13
作者:
Bu, Lihong
;
Ma, Xiaowei
;
Ji, Aiyan
;
Geng, Kaijun
;
Feng, Hongyan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
Mesenchymal epithelial transition receptor
Gliomas
[18F]-AZC
PET
Quinoline derivative compound
Discovery of novel cGAS inhibitors based on natural flavonoids
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 14
作者:
Li, Jiameng
;
Xiong, Muya
;
Liu, Jiayuan
;
Zhang, Fengping
;
Li, Minjun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Cyclic GMP-AMP synthase
Inhibitor
Flavonoids
Crystal structure
Virtual screening
Synthesis, and biological evaluation of EGFR/HER2-NAMPT conjugates for tumor treatment
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 20
作者:
Ding, Mengyuan
;
Shen, Qianqian
;
Lu, Wei
;
Zhu, Shulei
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2023/10/17
EGFR
HER2
NAMPT
Resistance
Selectivity
Molecular docking
Stimuli-activatable PROTACs for precise protein degradation and cancer therapy
期刊论文
OAI收割
SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 10, 页码: 1069-1085
作者:
Gao, Jing
;
Yang, Lei
;
Lei, Shumin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
PROTAC
Stimuli-activatable prodrug
Precise protein degradation
Nanomedicine
Combinatory therapy
Discovery of novel non-peptidic and non-covalent small-molecule 3CL(pro) inhibitors as potential candidate for COVID-19 treatment
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 4
作者:
Jiang, Zhidong
;
Feng, Bo
;
Zhang, Yumin
;
Nie, Tianqing
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13
作者:
Zhou, Ji
;
Zhang, Xu-Chao
;
Xue, Shan
;
Dai, Mengdi
;
Wang, Yueliang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17