中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
植物研究所 [8]
上海药物研究所 [4]
寒区旱区环境与工程研... [2]
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OAI收割 [18]
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期刊论文 [15]
学位论文 [3]
SCI/SSCI论文 [1]
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2023 [3]
2022 [2]
2020 [2]
2018 [2]
2017 [1]
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Plant Scie... [6]
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From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:
Zhou, Zehui
;
Zhou, Guizhen
;
Zhou, Chuan
;
Fan, Zisheng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190
作者:
Liu, Meiying
;
Zhou, Guizhen
;
Su, Wenhong
;
Gu, Yuejiao
;
Gao, Mingshan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/27
KRAS mutation
SOS1-KRAS interaction
SOS1 inhibitor
combination therapy
Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3923-3942
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Zhou, Zehui
;
Li, Yupeng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
A Ca2+-sensor switch for tolerance to elevated salt stress in Arabidopsis
期刊论文
OAI收割
DEVELOPMENTAL CELL, 2022, 卷号: 57, 期号: 17, 页码: 1-14
作者:
Steinhorst, Leonie
;
He, Gefeng
;
Moore, Lena K.
;
Schultke, Stefanie
;
Schmitz-Thom, Ina
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/07
The F-box protein EST1 modulates salt tolerance in Arabidopsis by regulating plasma membrane Na+/H+ antiport activity
期刊论文
OAI收割
JOURNAL OF PLANT PHYSIOLOGY, 2020, 卷号: 251
作者:
Liu, Jie
;
Lin, Qing Fang
;
Qi, Shi Lian
;
Feng, Xuan Jun
;
Han, Hui Ling
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/01/06
F-box protein
Salt tolerance
Na+/H+ antiporter
Mitogen-activated protein kinase
Arabidopsis thaliana
The F-box protein EST1 modulates salt tolerance in Arabidopsis by regulating plasma membrane Na+/H+ antiport activity
期刊论文
OAI收割
JOURNAL OF PLANT PHYSIOLOGY, 2020, 卷号: 251
作者:
Liu, Jie
;
Lin, Qing Fang
;
Qi, Shi Lian
;
Feng, Xuan Jun
;
Han, Hui Ling
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2022/03/01
F-box protein
Salt tolerance
Na+/H+ antiporter
Mitogen-activated protein kinase
Arabidopsis thaliana
Synergistic responses of NHX, AKT1, and SOS1 in the control of Na+ homeostasis in sweet sorghum mutants induced by C-12(6+)-ion irradiation
期刊论文
OAI收割
NUCLEAR SCIENCE AND TECHNIQUES, 2018, 卷号: 29, 期号: 1, 页码: 10
作者:
Qu, Ying
;
Dong, Xi-Cun
;
Jin, Wen-Jie
;
Liu, Rui-Yuan
;
Gu, Wen-Ting
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2018/05/31
C-12(6+)-ion irradiation
Sweet sorghum
Salt stress
NHX
AKT1
SOS1
Glutamate Receptor Homolog3.4 is Involved in Regulation o Seed Germination Under Salt Stress in Arabidopsis
期刊论文
OAI收割
PLANT AND CELL PHYSIOLOGY, 2018, 卷号: 59, 期号: 5, 页码: 978-988
作者:
Cheng, Yao
;
Zhang, Xiuxiu
;
Sun, Tianyang
;
Tian, Qiuying
;
Zhang, Wen-Hao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/02/25
Arabidopsis thaliana
AtGLR3.4
SOS pathway
Na accumulation
ABA
Salt stress
Seed germination
青海两种牧草对盐胁迫的响应
学位论文
OAI收割
硕士, 北京: 中国科学院研究生院, 2017
作者:
王建科
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2017/06/21
盐胁迫
紫花苜蓿
同德小花碱茅
种子萌发
SOS1