中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
高能物理研究所 [1]
海洋研究所 [1]
上海生物化学与细胞生... [1]
上海营养与健康研究所 [1]
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OAI收割 [10]
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期刊论文 [10]
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2022 [1]
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2018 [2]
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Discovery and Structure-Activity Relationship Studies of Thiazole-Oxazole Tandem Heterocyclic RNA Splicing Inhibitors
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 42, 期号: 9, 页码: 2925-2939
作者:
Zhang Rong
;
Gao Xiang
;
Chen Lingling
;
Nan Fajun
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/13
splicing inhibitors
circmCherry-expression system
Leucamide A derivatives
structure-activity relationships
DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing
期刊论文
OAI收割
CELL METABOLISM, 2021, 卷号: 33, 期号: 10, 页码: 2004-+
作者:
Li, Yufeng
;
Xu, Junyu
;
Lu, Yuting
;
Bian, Hua
;
Yang, Lin
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/18
Detection of PRMT1 inhibitors with stopped flow fluorescence
期刊论文
OAI收割
Signal transduction and targeted therapy, 2018, 卷号: 3, 页码: 6
作者:
Qian, Kun
;
Hu, Hao
;
Xu, Hui
;
Zheng, Y George
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
Nuclear PTEN safeguards pre-mRNA splicing to link Golgi apparatus for its tumor suppressive role
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2018, 卷号: 9, 期号: -, 页码: 2392
作者:
Shen, Shao-Ming
;
Zhang, Cheng
;
Yang, Shuo
;
Xiong, Zhong
;
Ge, Meng-Kai
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/12/09
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068
作者:
Wang, Gui-min
;
Wang, Xiang
;
Zhu, Jian-ming
;
Guo, Bin-bin
;
Yang, Zhuo
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
B-Raf(V600E) inhibitor
anticancer
vemurafenib
deazapurine
fragment reassembly
molecular docking
structure-activity relationship
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf~(V600E) inhibitors
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1057-1068
作者:
Wang Guimin
;
Wang Xiang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
B-Raf~(V600E) inhibitor
anticancer
vemurafenib
deazapurine
fragment reassembly
molecular docking
structure-activity relationship
Drug Discovery of Host CLK1 Inhibitors for Influenza Treatment
期刊论文
OAI收割
MOLECULES, 2015, 卷号: 20, 期号: 11, 页码: 19735-19747
作者:
Zu M(祖勉)
;
Zu, M
;
Li, C
;
Fang, JS
;
Lian, WW
收藏
  |  
浏览/下载:195/0
  |  
提交时间:2016/04/18
influenza A virus
CLK1 inhibitor
CPE assay
baculovirus coinfection
protein expression and purification
rational screening
Efficient synthesis of chloro-derivatives of sialosyllactosylceramide, and their enhanced inhibitory effect on epidermal growth factor receptor activation
期刊论文
OAI收割
ONCOLOGY LETTERS, 2014, 卷号: 7, 期号: 4, 页码: 933-940
作者:
Kawashima, Nagako
;
Qu, Huanhuan
;
Lobaton, Marlin
;
Zhu, Zhenyuan
;
Sollogoub, Matthieu
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
EGFR inhibitors
cell proliferation
EGFR activation
GM3
glycosphingolipids
chloro-derivatives of GM3
Basic anatomy and tumor biology of the RPS6KA6 gene that encodes the p90 ribosomal S6 kinase-4
期刊论文
OAI收割
ONCOGENE, 2013, 卷号: 32, 期号: 14, 页码: 1794-1810
作者:
Sun, Y.
;
Cao, S.
;
Yang, M.
;
Wu, S.
;
Wang, Z.
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2014/07/17
PRS6KA6
RSK4
alternative splicing
breast cancer
pancreatic cancer
aPKC inhibitors might be the sensitizer of chemotherapy and adoptive immunotherapy in the treatment of hASIPa - Overexpressed breast cancer
期刊论文
OAI收割
ONCOLOGY RESEARCH, 2008, 卷号: 17, 期号: 2, 页码: 59-68
作者:
Jin, YT
;
Ying, XX
;
Hu, YH
;
Zou, Q
;
Wang, HY
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2015/07/22
human breast cancer
hASIP
aPKC inhibitor
5-FU
DCIK/DCIK-P cells