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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [95]
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OAI收割 [95]
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期刊论文 [91]
会议论文 [2]
学位论文 [2]
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2022 [5]
2020 [2]
2019 [7]
2018 [7]
2016 [4]
2013 [4]
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专题:上海药物研究所
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Computationally Elucidating the Binding Kinetics for Different AChE Inhibitors to Access the Rationale for Improving the Drug Efficacy
期刊论文
OAI收割
JOURNAL OF PHYSICAL CHEMISTRY B, 2022, 页码: 9
作者:
Bai, Fang
;
Jiang, Hualiang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/11/11
Water-soluble non-conjugated polymer dots with strong green fluorescence for sensitive detection of organophosphate pesticides
期刊论文
OAI收割
ANALYTICA CHIMICA ACTA, 2022, 卷号: 1206, 页码: 9
作者:
Zhang, Chunxian
;
Li, Shuai
;
Duan, Zhiqiang
;
Li, Qin
;
Zhao, Mengxuan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/08/16
Water-soluble polymer dots
MnO2 nanosheets
Fluorimetric detection
Catalysis inhibition
Organophosphate pesticides
Novel inhibitors of AChE and A0 aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235, 页码: 22
作者:
Liu, Yulin
;
Uras, Giuseppe
;
Onuwaje, Itse
;
Li, Wenlong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/08/16
Alzheimer's disease
Donepezil
Sulfone group
AChE inhibitor
Inhibiting A 0 aggregation
Neuroprotection
Caulophyine A, a Rare Azapyrene Alkaloid from the Roots of Caulophyllum robustum
期刊论文
OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2022, 卷号: 70, 期号: 4, 页码: 283-285
作者:
Wei, Wei
;
Yuan, Ya-Hong
;
Jiao, Fu-Rong
;
Zhao, Xiang
;
Xiao, Lei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
Caulophyllum robustum
alkaloid
azapyrene
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
期刊论文
OAI收割
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 页码: 16
作者:
Zeng, Yan
;
Nie, Lifei
;
Liu, Liu
;
Niu, Chao
;
Li, Yi
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/15
Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855
作者:
Zhou, Yu
;
Fu, Yan
;
Yin, Wanchao
;
Li, Jian
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
[1,5]-Hydride Shift-Cyclization versus C(sp(2))-H Functionalization in the Knoevenagel-Cyclization Domino Reactions of 1,4-and 1,5-Benzoxazepines
期刊论文
OAI收割
MOLECULES, 2020, 卷号: 25, 期号: 6, 页码: 19
作者:
Vargane, Dora Szaloki
;
Toth, Laszlo
;
Buglyo, Balazs
;
Kiss-Szikszai, Attila
;
Mandi, Attila
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
domino Knoevenagel-[1
5]-hydride shift-cyclization
1
4-benzoxazepine
1
5-benzoxazepine
TDDFT-ECD calculation
acetylcholinesterase inhibitory activity
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening
期刊论文
OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:
Liu, Guangpu
;
Jiao, Yang
;
Lin, Yongqiang
;
Hao, Haifang
;
Dou, Yanli
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
selective acetylcholinesterase inhibitor
amyloid beta aggregation
neuroprotectant
molecular docking
molecular dynamics simulation
Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1386-1393
作者:
Cui, Xue
;
Guo, Yu-e
;
Fang, Jia-hui
;
Shi, Chang-jie
;
Suo, Na
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
donepezil
aricept
oligodendrocyte
oligodendrocyte progenitor cell
differentiation
myelin sheaths
remyelination
CNS demyelinating disorders
multiple sclerosis
Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity
期刊论文
OAI收割
FITOTERAPIA, 2019, 卷号: 139, 页码: 7
作者:
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Lycopodiastrum casuarinoides
Lycopodiaceae
Lycodine-type alkaloids
TD-DFT
ECD