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Novel inhibitors of AChE and A0 aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235, 页码: 22
作者:  Liu, Yulin;  Uras, Giuseppe;  Onuwaje, Itse;  Li, Wenlong;  Yao, Hong
  |  收藏  |  浏览/下载：28/0  |  提交时间：2022/08/16
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease 期刊论文  OAI收割
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 页码: 16
作者:  Zeng, Yan;  Nie, Lifei;  Liu, Liu;  Niu, Chao;  Li, Yi
  |  收藏  |  浏览/下载：27/0  |  提交时间：2022/06/15
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:  Li, Xiaokang;  Li, Jinwen;  Huang, Yunyuan;  Gong, Qi;  Fu, Yan
  |  收藏  |  浏览/下载：31/0  |  提交时间：2022/06/15
Desorption electrospray ionization (DESI) source coupling ion mobility mass spectrometry for imaging fluoropezil (DC20) distribution in rat brain 期刊论文  OAI收割
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 页码: 13
作者:  Guo, Runcong;  Zhou, Lei;  Chen, Xiaoyan
  |  收藏  |  浏览/下载：17/0  |  提交时间：2021/11/04
Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855
作者:  Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei
  |  收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening 期刊论文  OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:  Liu, Guangpu;  Jiao, Yang;  Lin, Yongqiang;  Hao, Haifang;  Dou, Yanli
  |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1386-1393
作者:  Cui, Xue;  Guo, Yu-e;  Fang, Jia-hui;  Shi, Chang-jie;  Suo, Na
  |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01
Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation 期刊论文  OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Wang, Yin-Yin;  Tao, Hong-Rui
  |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01
Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation 期刊论文  OAI收割
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 5, 页码: 521-530
作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Song, Jia-Li;  Wang, Yin-Yin
  |  收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01
donepeziladrugforalzheimersdiseasepromotesoligodendrocytegenerationandremyelination 期刊论文  OAI收割
actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1386
作者:  Cui Xue;  Guo Yue;  Fang Jiahui;  Shi Changjie;  Suo Na
  |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01