中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [44]
采集方式
OAI收割 [44]
内容类型
期刊论文 [44]
发表日期
2023 [3]
2022 [12]
2021 [2]
2020 [6]
2019 [3]
2018 [4]
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专题:上海药物研究所
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Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11
作者:
Zhao, Yitian
;
Zhang, Min
;
Hou, Xudong
;
Han, Jiaxin
;
Qin, Xiaoya
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Salicylanilide
hPL inhibitor
Structure -activity relationship
Anti -obesity
Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16
作者:
He, Yulong
;
Li, Shunyi
;
Zhu, Yueyue
;
Wang, Yujie
;
Chen, Yuqi
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2023/10/17
Structure-activity relationship
FABP4 inhibitor
Biphenyl scaffold
Selectivity
Oral bioavailability
Anti-inflammation
14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 2, 页码: 434
作者:
Chen Jiali
;
Feng Zheling
;
Zhou Fei
;
Lou Ruohan
;
Peng Cheng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/05/22
14-deoxygarcinol
adipose tissue inflammation
insulin resistance
interleukin-1β
NLRP3 inflammasome
Sirtuin 2
Limosilactobacillus reuteri and caffeoylquinic acid synergistically promote adipose browning and ameliorate obesity-associated disorders
期刊论文
OAI收割
MICROBIOME, 2022, 卷号: 10, 期号: 1, 页码: 22
作者:
Liu, Yameng
;
Zhong, Xianchun
;
Lin, Suqin
;
Xu, Hualing
;
Liang, Xinyu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Obesity
Prebiotic
Probiotics
Short-chain fatty acids
Propionate
Thermogenesis
Browning
Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2022, 页码: 20
作者:
Feng, Zheling
;
Chen, Jiali
;
Chen, Cheng
;
Feng, Lu
;
Wang, Rui
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
anti-obesity
bioactivity-based molecular networking
Garcinia cambogia
guttiferone J
sirtuin 3
white adipose tissue browning
Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1
作者:
Deng,Xu
;
Huang,Su-Ling
;
Ren,Jian
;
Pan,Zheng-Hong
;
Shen,Yu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure–activity relationships
Development and structure-activity relationships of tanshinones as selective 11beta-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural products and bioprospecting, 2022, 卷号: 12, 期号: 1, 页码: 36
作者:
Deng, Xu
;
Huang, Su-Ling
;
Ren, Jian
;
Pan, Zheng-Hong
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/15
Metabolic syndrome
Selective 11beta-HSD1 inhibitors
Structure-activity relationships
Tanshinones
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14
作者:
Huang, Su-Ling
;
Xie, Wei
;
Ye, Yang-Liang
;
Liu, Jia
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/11/11
type 2 diabetes mellitus
coronarin A
glycogen synthesis
gluconeogenesis
mTORC1
IRS1
Therapeutic potential of traditional Chinese medicine for the treatment of NAFLD: A promising drug Potentilla discolor Bunge
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 9, 页码: 3529-3547
作者:
Ji, Longshan
;
Li, Qian
;
He, Yong
;
Zhang, Xin
;
Zhou, Zhenhua
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/13
Anti-inflammatory
Lipid metabolism
Insulin resistance
Endoplasmic reticulum stress
Intestinal microflora
Nonalcoholic fatty liver disease (NAFLD)
Traditional Chinese medicine
Acupuncture
Potentilla discolor Bunge (PDB)
Natural active compounds
Anti-oxidative
14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-kappa B/Sirtuin 2-NLRP3-mediated adipose tissue remodeling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Chen, Jia-li
;
Feng, Zhe-ling
;
Zhou, Fei
;
Lou, Ruo-han
;
Peng, Cheng
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/09/30
14-deoxygarcinol
adipose tissue inflammation
insulin resistance
interleukin-1 beta
NLRP3 inflammasome
Sirtuin 2