机构

• 上海药物研究所 [14]
• 合肥物质科学研究院 [2]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [16]

发表日期

• 2022 [16]

学科主题

筛选

浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2022     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells 期刊论文  OAI收割 MOLECULAR CANCER RESEARCH, 2022, 卷号: 20, 期号: 12, 页码: 1785-1798 作者:  Sun, Lin;  Wu, Qian;  Huan, Xia-Juan;  Tian, Chang-Qing;  Wang, Ying-Qing   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 Proteomic characterization of post-translational modifications in drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 18 作者:  Zhai, Lin-hui;  Chen, Kai-feng;  Hao, Bing-bing;  Tan, Min-jia   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/04/10 proteomics  protein post-translational modification  drug target  off-target  drug mechanism  precision medicine   Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13 作者:  Luo, Menglan;  Wu, Qian;  Yang, Yueyue;  Sun, Lin;  Huan, Xiajuan   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/30 BET inhibitor  BRD4  Bivalent inhibitor  Anticancer   BPTF inhibition antagonizes colorectal cancer progression by transcriptionally inactivating Cdc25A 期刊论文  OAI收割 REDOX BIOLOGY, 2022, 卷号: 55, 页码: 16 作者:  Guo, Ping;  Zu, Shijia;  Han, Shilong;  Yu, Wendan;  Xue, Guoqing   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/12/13 Colorectal cancer  BPTF  Cdc25A  c-Myc  Cell cycle   Phosphoproteomics Reveals the AMPK Substrate Network in Response to DNA Damage and Histone Acetylation 期刊论文  OAI收割 GENOMICS PROTEOMICS & BIOINFORMATICS, 2022, 卷号: 20, 期号: 4, 页码: 597-613 作者:  Jiang, Yuejing;  Cong, Xiaoji;  Jiang, Shangwen;  Dong, Ying;  Zhao, Lei   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 AMPK  Phosphoproteomics  Histone modification  DNA damage  Apoptosis   Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16 作者:  Chen, Zonglong;  Li, Jiayi;  Yang, Hong;  He, Yulong;  Shi, Qiongyu   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/08/16 P300  Bromodomain inhibitors  CBP30  SBDD   Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15 作者:  Liu, Ruiqi;  Yang, Hong;  Chen, Zonglong;  Zhou, Kaixin;  Shi, Qiongyu   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 Epigenetics  p300  CBP  Bromodomain inhibitors  CCS1477   Discovery of CECR2 Bromodomain Inhibitors with High Selectivities over BPTF Bromodomain 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 2072-2080 作者:  Lu, Haibo;  Zu, Shijia;  Duan, Zhe;  Feng, Yueyao;  Wang, Jie   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/08/16 CECR2 bromodomain  BPTF bromodomain  Inhibitors  Structure-activity relationships  chemical probe   Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 14 作者:  Chen, Jingjing;  He, Huixin;  Wei, Aihuan;  Li, Yalei;  Cheng, Gang   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 PROTAC  Pyrrolopyridone  BRD4 S  Selectivity   Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 123, 页码: 12 作者:  Lu, Haibo;  Lu, Tian;  Zu, Shijia;  Duan, Zhe;  Guang, Yiman   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/08/16 CECR2 bromodomain  BPTF bromodomain  Small-molecule inhibitor  SAR study  Chemical probe