机构

• 上海药物研究所 [21]

采集方式

• OAI收割 [21]

内容类型

• 期刊论文 [21]

发表日期

• 2022 [1]
• 2020 [1]
• 2018 [2]
• 2017 [2]
• 2015 [1]
• 2014 [1]
• 更多

学科主题

• Biochemist... [1]
• Biotechnol... [1]
• Mathematic... [1]

筛选

浏览/检索结果: 共21条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 38, 页码: 9 作者:  Hart, Jonathan R.;  Liu, Xiao;  Pan, Chen;  Liang, Anyi;  Ueno, Lynn   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 phosphoinositide 3-kinase (PI3K)  nanobody  conformational changes  chemical cross-linking  mass spectrometry   Unveiling conformational dynamics changes of H-Ras induced by mutations based on accelerated molecular dynamics 期刊论文  OAI收割 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2020, 卷号: 22, 期号: 37, 页码: 21238-21250 作者:  Chen, Jianzhong;  Wang, Wei;  Pang, Laixue;  Zhu, Weiliang   |  收藏  |  浏览/下载：13/0  |  提交时间：2020/12/21 Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文  OAI收割 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305 作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang   |  收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08 allosteric inhibitor  HIV-1 protease  MM-GBSA  normal mode analysis  REMD   Structure of the glucagon receptor in complex with a glucagon analogue 期刊论文  OAI收割 NATURE, 2018, 卷号: 553, 期号: 7686, 页码: 106-+ 作者:  Zhang, Haonan;  Qiao, Anna;  Yang, Linlin;  Van Eps, Ned;  Frederiksen, Klaus S.   |  收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling 期刊论文  OAI收割 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248 作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Energetics and structural characterization of the "DFG-flip'' conformational transition of B-RAF kinase: a SITS molecular dynamics study 期刊论文  OAI收割 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 2, 页码: 1257-1267 作者:  Shao, Qiang;  Xu, Zhijian;  Wang, Jinan;  Shi, Jiye;  Zhu, Weiliang   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Increasing the sampling efficiency of protein conformational transition using velocity-scaling optimized hybrid explicit/ implicit solvent REMD simulation 期刊论文  OAI收割 JOURNAL OF CHEMICAL PHYSICS, 2015, 卷号: 142, 期号: 12 作者:  Yu, Yuqi;  Wang, Jinan;  Shao, Qiang;  Shi, Jiye;  Zhu, Weiliang   |  收藏  |  浏览/下载：7/0  |  提交时间：2019/01/08 Mapping Central alpha-Helix Linker Mediated Conformational Transition Pathway of Calmodulin via Simple Computational Approach 期刊论文  OAI收割 JOURNAL OF PHYSICAL CHEMISTRY B, 2014, 卷号: 118, 期号: 32, 页码: 9677-9685 作者:  Wang, Jinan;  Peng, Shaoliang;  Cossins, Benjamin P.;  Liao, Xiangke;  Chen, Kaixian   |  收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08 Solution structure and backbone dynamics of human Raf-1 kinase inhibitor protein 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 卷号: 438, 期号: 1, 页码: 129-132 作者:  Guo, Chenyun;  Yi, Cuiying;  Peng, Yu;  Wen, Yi;  Lin, Donghai   |  收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08 Human Raf-1 kinase inhibitor protein (hRKIP)  Solution structure  Ligand-binding pocket  NMR  Model-free analysis  Protein dynamics   Highly Crystalline Forms of Valsartan with Superior Physicochemical Stability 期刊论文  OAI收割 CRYSTAL GROWTH & DESIGN, 2013, 卷号: 13, 期号: 7, 页码: 3261-3269 作者:  Wang, Jian-Rong;  Wang, Xiaojuan;  Lu, Liye;  Mei, Xuefeng   |  收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08