机构

• 上海药物研究所 [10]
• 生态环境研究中心 [2]
• 近代物理研究所 [1]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [12]
• 专著章节 [1]

发表日期

• 2019 [13]

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2019     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Common activation mechanism of class A GPCRs 期刊论文  OAI收割 ELIFE, 2019, 卷号: 8, 页码: 31 作者:  Zhou, Qingtong;  Yang, Dehua;  Wu, Meng;  Guo, Yu;  Guo, Wangjing   |  收藏  |  浏览/下载：76/0  |  提交时间：2020/07/01 A complex structure of arrestin-2 bound to a G protein-coupled receptor 期刊论文  OAI收割 CELL RESEARCH, 2019, 卷号: 29, 期号: 12, 页码: 971-983 作者:  Yin, Wanchao;  Li, Zhihai;  Jin, Mingliang;  Yin, Yu-Ling;  de Waal, Parker W.   |  收藏  |  浏览/下载：59/0  |  提交时间：2020/07/01 DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening 期刊论文  OAI收割 GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495 作者:  Wan, Fangping;  Zhu, Yue;  Hu, Hailin;  Dai, Antao;  Cai, Xiaoqing   |  收藏  |  浏览/下载：63/0  |  提交时间：2020/07/01 Deep learning  Machine learning  Drug discovery  In silico drug screening  Compound-protein interaction prediction   Chapter 1 - Progress in GPCR structure determination 专著章节  OAI收割 出自: GPCRs: Structure, Function, and Drug Discovery, 125 London Wall, London EC2Y 5AS, United Kingdom:Academic Press, 2019 作者:  Qu, Xiangli;  Wang, Dejian;  Wu, Beili   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/14 Ligand-induced activation of ERK1/2 signaling by constitutively active G(s)-coupled 5-HT receptors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1157-1167 作者:  Liu, Ping;  Yin, Yu-ling;  Wang, Ting;  Hou, Li;  Wang, Xiao-xi   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 5-HT4R  5-HT6R  5-HT7AR  5-HT  ERK1/2  G(s)  beta-arrestin  Fyn  Src   Uncovering kappa-opioid receptor agonist-induced PAK1/2 phosphorylation by quantitative phosphoproteomics 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 516, 期号: 1, 页码: 320-326 作者:  Wu, Jianhong;  Jiang, Qinghui;  Zhu, Hongwen;  Zhou, Yanting;  Lu, Dayun   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 Dimethyl labeling  Kappa-opioid receptor  Kinase-substrate network  p21-activated kinases  Quantitative phosphoproteomics   A Chemical Strategy for Amphiphile Replacement in Membrane Protein Research 期刊论文  OAI收割 LANGMUIR, 2019, 卷号: 35, 期号: 12, 页码: 4319-4327 作者:  Xue, Dongxian;  Wang, Jingjing;  Song, Xiyong;  Wang, Wei;  Hu, Tao   |  收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01 Advancing Chemokine GPCR Structure Based Drug Discovery 期刊论文  OAI收割 STRUCTURE, 2019, 卷号: 27, 期号: 3, 页码: 405-408 作者:  Zhao, Suwen;  Wu, Beili;  Stevens, Raymond C.   |  收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the kappa-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 3, 页码: 1575-1584 作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Zhou, Shuangyan;  Shi, Danfeng   |  收藏  |  浏览/下载：57/0  |  提交时间：2019/11/10 kappa-opioid receptor  Gaussian accelerated molecular dynamics simulation  agonist  antagonist  conformational change   Vincamine as a GPR40 agonist improves glucose homeostasis in type 2 diabetic mice 期刊论文  OAI收割 JOURNAL OF ENDOCRINOLOGY, 2019, 卷号: 240, 期号: 2, 页码: 195-214 作者:  Du, Te;  Yang, Liu;  Xu, Xu;  Shi, Xiaofan;  Xu, Xin   |  收藏  |  浏览/下载：102/0  |  提交时间：2019/01/08 vincamine  GPR40  beta-cell function  insulin secretion  type 2 diabetes