中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
昆明植物研究所 [2]
合肥物质科学研究院 [2]
水生生物研究所 [1]
重庆绿色智能技术研究... [1]
采集方式
OAI收割 [10]
内容类型
期刊论文 [9]
学位论文 [1]
发表日期
2021 [10]
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发表日期:2021
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
OAI收割
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Rhubarb granule promotes diethylnitrosamine-induced liver tumorigenesis by activating the oxidative branch of pentose phosphate pathway via G6PD in rats
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 281
作者:
Huang, Hongwu
;
Liu, Zhenzhen
;
Qi, Xiaoru
;
Gao, Nailong
;
Chang, Jianguo
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/11/15
Rhubarb
Hepatocarcinogenesis
Diethylnitrosamine
The pentose phosphate pathway
Glucose 6 phosphate dehydrogenase
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro
期刊论文
OAI收割
ENVIRONMENTAL TOXICOLOGY, 2021
作者:
Wang, Caixia
;
Gu, Zhangyu
;
Gu, Xueyan
;
Tan, Xinyue
;
Wang, Shuang
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/01
hepatotoxicity
mitochondrial apoptosis
Nano-Se
nickel
PI3K-Akt pathway
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
OAI收割
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
雷公藤制剂肝毒性的机制及其调节作用研究
学位论文
OAI收割
2021
作者:
彭婉
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/20
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Chronic exposure to PPCPs mixture at environmentally relevant concentrations (ERCs) altered carbohydrate and lipid metabolism through gut and liver toxicity in zebrafish
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 10
作者:
Hamid, Naima
;
Junaid, Muhammad
;
Wang, Yan
;
Pu, Shi-Ya
;
Jia, Pan-Pan
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/17
Hepatotoxicity
Gut homeostasis
Chronic exposure
Lipid metabolism
Zebrafish
An identified PfHMGB1 promotes microcystin-LR-induced liver injury of yellow catfish (Pelteobagrus fulvidraco)
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 207, 页码: 11
作者:
Wang, Yun
;
Xiao, Xiaoxue
;
Wang, Feijie
;
Yang, Zupeng
;
Yue, Jingkai
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2021/01/15
PfHMGB1
MC-LR
Hepatotoxicity
Liver injury
Yellow catfish
anti-PfHMGB1
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations
期刊论文
OAI收割
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:
Peng,Wan
;
Dai,Man-Yun
;
Bao,Li-Juan
;
Zhu,Wei-Feng
;
Li,Fei
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/04/02
Tripterygium wilfordii
liver injury
farnesoid X receptor
bile acid metabolism
metabolomics
Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 870-881
作者:
Pang, Xiaoyan
;
Tang, Chongzhuang
;
Cao, Peng
;
Zhou, Lei
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/06/15
Retrorsine
bile acid
oxidative stress
reactive metabolite
transporter
Nrf2