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合肥物质科学研究院 [40]
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期刊论文 [612]
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Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Robust optimisation of the streamlined shape of a high-speed train in crosswind conditions
期刊论文
OAI收割
ENGINEERING APPLICATIONS OF COMPUTATIONAL FLUID MECHANICS, 2023, 卷号: 17, 期号: 1, 页码: 2234012
作者:
Wang YT(王业腾)
;
Sun ZX(孙振旭)
;
Ju SJ(鞠胜军)
;
Guo DL(郭迪龙)
;
Yang GW(杨国伟)
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/09/05
Railway aerodynamic
High-speed train
Crosswind
Robust optimisation
Flow structures
>
Diversity of strong negative Indian Ocean dipole events since 1980: characteristics and causes
期刊论文
OAI收割
CLIMATE DYNAMICS, 2023, 页码: 24
作者:
Huang, Ke
;
Huang, Bohua
;
Wang, Dongxiao
;
Zhao, Xia
;
Zhang, Lianyi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/07
Indian Ocean dipole
Air-sea interaction
Inter-annual variability
Bjerknes feedback
La Nina
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
DeepHipp: accurate segmentation of hippocampus using 3D dense-block based on attention mechanism
期刊论文
OAI收割
BMC MEDICAL IMAGING, 2023, 卷号: 23, 期号: 1, 页码: 15
作者:
Wang, Han
;
Lei, Cai
;
Zhao, Di
;
Gao, Liwei
;
Gao, Jingyang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/04
Segmentation of hippocampus
Deep learning
Dense block, Attention, Data augmentation
Mechanisms of lead uptake and accumulation in wheat grains based on atmospheric deposition-soil sources
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 885, 页码: 163845
作者:
Ma, Chuang
;
Lin, Lin
;
Yang, Junxing
;
Liu, Fuyong
;
Berrettoni, Mario
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/07/14
Wheat
Pb
Translocation
Node
Hindering effect
Late-Stage Functionalization for the Divergent Synthesis of Podophyllotoxin Derivatives by Rhodium Catalysis
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 10
作者:
Zhao, Yue
;
Shen, Yangpeng
;
He, Jian
;
Li, Jing
;
Zhou, Shengbin
  |  
收藏
  |  
浏览/下载:138/0
  |  
提交时间:2023/10/17
anticancer
C-H bond activation
divergent synthesis
podophyllotoxin
late-stage functionalization
Stabilization of Pb(II) in wastewater and tailings by commercial bacteria through microbially induced phosphate precipitation (MIPP)
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 868
作者:
Han, Li-Jun
;
Li, Jiang -Shan
;
Chen, Zhen
;
Xue, Qiang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/08/02
Commercial bacterium
bacillus subtilis
Microbially induced phosphate precipitation (MIPP)
Pb(II) removal
Wastewater
Lead-zinc tailings
Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 88, 期号: 6, 页码: 3808-3821
作者:
Zhu, Huajian
;
Wang, Jiang
;
Lu, Yunfu
;
Soloshonok, Vadim A.
;
Lan, Lefu
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
Acute low-dose phosphate disrupts glycerophospholipid metabolism and induces stress in juvenile turbot (Scophthalmus maximus)
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 861, 页码: 12
作者:
Qi, Ting
;
Wu, Lele
;
Yu, Jiachen
;
Song, Zongcheng
;
Liu, Feng
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/13
Phosphate
Toxicity
Metabolomics
Histopathological damage
Gene expression