中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [78]
采集方式
OAI收割 [78]
内容类型
期刊论文 [76]
会议论文 [2]
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2024 [1]
2023 [2]
2022 [4]
2021 [2]
2020 [3]
2019 [5]
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浏览/检索结果:
共78条,第1-10条
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专题:上海药物研究所
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Meta-MolNet: A Cross-Domain Benchmark for Few Examples Drug Discovery
期刊论文
OAI收割
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2024, 页码: 15
作者:
Lv, Qiujie
;
Chen, Guanxing
;
Yang, Ziduo
;
Zhong, Weihe
;
Chen, Calvin Yu-Chian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
Benchmark platform
cross-domain meta-learning
drug discovery
few examples
Meta-MolNet
molecular property
Pharmacokinetic and metabolite profile of orally administered anemoside B4 in rats with an improved exposure in formulations of rectal suppository
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 315, 页码: 11
作者:
Ye, Yaqing
;
Xue, Mingzhen
;
Tian, Xiaoting
;
Gao, Hongwei
;
Hu, Pei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Anemoside B4
Pulsatilla chinensis
metabolite identification
Pharmacokinetics
Rectal suppository
Development and validation of a LC-MS/MS method for quantitation of recombinant human growth hormone in rat plasma and application to a pharmacokinetic study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 224, 页码: 9
作者:
Huang, Wen-si
;
Yu, Jing-hua
;
Diao, Xing-xing
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
Recombinant human growth hormone (rhGH)
Somatotropin
Method validation
LC-MS
MS
Pharmacokinetics
Enzyme-linked immunosorbent assays for quantification of MMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2022, 卷号: 12, 期号: 4, 页码: 645-652
作者:
Pei, Min
;
Liu, Tingting
;
Ouyang, Lu
;
Sun, Jianhua
;
Deng, Xiaojie
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/11/11
Monomethyl auristatin E
Antibody-drug conjugates
Pharmacokinetics
Trophoblast cell surface antigen 2
iTRAQ-based quantitative proteomics reveals biomarkers/pathways in psoriasis that can predict the efficacy of methotrexate
期刊论文
OAI收割
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2022, 页码: 12
作者:
Yan, K. X.
;
Meng, Q.
;
He, H.
;
Zhu, H. W.
;
Wang, Z. C.
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
LC-MS/MS assay of fluoropezil and its two major metabolites in human plasma: an application to pharmacokinetic studies
期刊论文
OAI收割
BIOANALYSIS, 2022, 页码: 13
作者:
Guo, Runcong
;
Hu, Jiafeng
;
Jing, Jiao
;
Liu, Ying
;
Li, Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
assay
bioanalysis
DC20
fluoropezil
LC-MS
MS
metabolites
pharmacokinetics
Development and validation of a liquid chromeatography-tandem mass spectrometry method for simultaneous quantification of medium- and long-chain saturated fatty acids in hamster plasma samples
期刊论文
OAI收割
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2022, 卷号: 36, 期号: 11, 页码: 11
作者:
Li, Fan
;
Zhang, Qingli
;
Tong, Yue
;
Jiang, Jianlan
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
A hybrid framework for improving uncertainty quantification in deep learning-based QSAR regression modeling
期刊论文
OAI收割
JOURNAL OF CHEMINFORMATICS, 2021, 卷号: 13, 期号: 1, 页码: 17
作者:
Wang, Dingyan
;
Yu, Jie
;
Chen, Lifan
;
Li, Xutong
;
Jiang, Hualiang
  |  
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2021/11/04
Uncertainty quantification
Quantitative structure-activity relationship
Bayesian neural network
Applicability domain
Bayesian inference
Error prediction
Artificial intelligence
Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2021, 卷号: 11, 期号: 4, 页码: 472-479
作者:
Gao, Yuxiong
;
Chen, Zhendong
;
Yang, Changyong
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/04
Anti-sclerostin monoclonal antibody (SHR-1222)
LC-MS/MS
Anti-drug antibody
Toxicokinetic
A rapid and convenient derivatization method for quantitation of short-chain fatty acids in human feces by ultra-performance liquid chromatography/tandem mass spectrometry
期刊论文
OAI收割
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2020, 卷号: 34, 期号: 9, 页码: 11
作者:
Fu, Huan
;
Zhang, Qing-li
;
Huang, Xiao-wu
;
Ma, Zheng-hua
;
Zheng, Xiao-li
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01