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Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2 期刊论文  OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:  Liu, Yaowen;  Nie, Tianqing;  Hou, Jinjun;  Long, Huali;  Zhang, Zijia
  |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/13
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds 期刊论文  OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2024, 卷号: 64, 期号: 3, 页码: 724-736
作者:  Ma, Minfei;  Zhang, Xinben;  Zhou, Liping;  Han, Zijian;  Shi, Yulong
  |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/13
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11
Repurposing of Rutan showed effective treatment for COVID-19 disease 期刊论文  OAI收割
FRONTIERS IN MEDICINE, 2023, 卷号: 10, 页码: 13
作者:  Salikhov, Shavkat I.;  Abdurakhmonov, Ibrokhim Y.;  Oshchepkova, Yuliya I.;  Ziyavitdinov, Jamolitdin F.;  Berdiev, Nodir Sh.
  |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan
  |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25
Elucidation of N-/O-glycosylation and site-specific mapping of sialic acid linkage isomers of SARS-CoV-2 human receptor angiotensin-converting enzyme 2 期刊论文  OAI收割
ANALYST, 2023, 卷号: 148, 期号: 20, 页码: 5002-5011
作者:  Wei, Liming;  Chen, Yuning;  Feng, Xiaoxiao;  Yao, Jun;  Zhang, Lei
  |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10
作者:  Zhang, Yumin;  Sun, Yuan;  Xie, Yuanchao;  Shang, Weijuan;  Wang, Zhen
  |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/08
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:  Yang, Hanxi;  You, Mengyuan;  Shu, Xiaoyang;  Zhen, Jingyao;  Zhu, Mengwei
  |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes 期刊论文  OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:  Sun, Zengchao;  Wang, Lu;  Li, Lingyun;  Sun, Yili;  Zhang, Daizhou
  |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17
Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial 期刊论文  OAI收割
LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13
作者:  Wang, Fuxiang;  Xiao, Wen;  Tang, Yimin;  Cao, Mengli;  Shu, Dan
  |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17