中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [47]
海洋研究所 [10]
西北高原生物研究所 [8]
烟台海岸带研究所 [7]
心理研究所 [6]
合肥物质科学研究院 [4]
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OAI收割 [87]
内容类型
期刊论文 [85]
学位论文 [2]
发表日期
2023 [87]
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Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
Inhibiting Endothelial Cell-Mediated T Lymphocyte Apoptosis with Integrin-Targeting Peptide-Drug Conjugate Filaments for Chemoimmunotherapy of Triple-Negative Breast Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2023, 页码: 12
作者:
Cai, Ying
;
Zhu, Binyu
;
Shan, Xiaoting
;
Zhou, Lingli
;
Sun, Xujie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
Fas ligand
immunotherapy
peptide-drug conjugate
triple-negative breast cancer
tumor-associated endothelial cells
Biocompatible Ferrofluid-Based Millirobot for Tumor Photothermal Therapy in Near-Infrared-II Window
期刊论文
OAI收割
ADVANCED HEALTHCARE MATERIALS, 2023, 页码: 12
作者:
Ji, Yiming
;
Bai, Xue
;
Sun, Hongyan
;
Wang, Luyao
;
Gan, Chunyuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/22
ferrofluid robots
biocompatibility
targeted therapy
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+
作者:
Xiao, Yufeng
;
Hale, Seth
;
Awasthee, Nikee
;
Meng, Chengcheng
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/16
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Autophagy contributes to increase the content of intracellular free amino acids in hard clam
(Mercenaria
mercenaria)
during prolonged exposure to hypersaline environments
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 192, 页码: 11
作者:
Zhou, Cong
;
Yang, Mei-jie
;
Hu, Zhi
;
Zou, Yan
;
Shi, Pu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/30
Hyposalinity
Hypersalinity
Transcriptome
Autophagy
Free amino acids
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors