中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [40]
过程工程研究所 [4]
合肥物质科学研究院 [2]
自动化研究所 [1]
采集方式
OAI收割 [47]
内容类型
期刊论文 [46]
项目 [1]
发表日期
2022 [47]
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Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Shi, Wei
;
Zhang, Jianxin
;
Liu, Liya
;
Li, Wanzhen
;
Liu, Zhi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540
作者:
Xie, Xiong
;
Zheng, Yu-Gui
;
Chen, Huan
;
Li, Jian
;
Luo, Rong-Hua
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Editorial: Pharmacokinetics of herbal medicines and herb-drug interactions
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 3
作者:
Jia, Wei-Wei
;
Lu, Chuang
;
Lin, Ge
;
Ge, Guang-Bo
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
herbal medicine
pharmacokinetics
drug combination
drug interaction
molecular mechanism
drug transporter
drug-metabolizing enzyme
Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
;
Wang, Hong
;
Qin, Hua
;
Guo, Zitao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids
Multi-compound and drug-combination pharmacokinetic research on Chinese herbal medicines
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 12, 页码: 3080-3095
作者:
Li, Chuan
;
Jia, Wei-wei
;
Yang, Jun-ling
;
Cheng, Chen
;
Olaleye, Olajide E.
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/21
Chinese herbal medicine
pharmacokinetics
multi-compound pharmacokinetic research
drug-combination pharmacokinetic research
pharmacokinetic compatibility
Population Pharmacokinetics of Tacrolimus in Pediatric Patients With Umbilical Cord Blood Transplant
期刊论文
OAI收割
JOURNAL OF CLINICAL PHARMACOLOGY, 2022
作者:
Zuo, Meiling
;
Shang, Yue
;
Guo, Ye
;
Sun, Yuxuan
;
Xu, Gaoqi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/12/23
Smart drug delivery systems for precise cancer therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4098-4121
作者:
Wang, Xiaoyou
;
Li, Chong
;
Wang, Yiguang
;
Chen, Huabing
;
Zhang, Xinxin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
Pharmaceutics
Smart drug delivery system
Stimuli-responsive
Receptor-ligand-based delivery
Nano-drug delivery systems
Precise therapy
Toxicity
Cancer
Absorption, distribution, metabolism, and excretion of [C-14]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 页码: 12
作者:
Li, Xin-mei
;
Zheng, Yuan-dong
;
Zhang, Yi-fan
;
Huan, Xia-juan
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13
[C-14]Mefuparib
Mefuparib (CVL218)
Blood-brain barrier
Mass balance
Tissue distribution
GastroPlus simulation
Multiple-dose up-titration study to evaluate the pharmacokinetics, safety and antitumor activity of apatinib in advanced gastric adenocarcinoma
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12, 页码: 10
作者:
Wang, Yonggang
;
Wang, Chang
;
Zhang, Yanqiao
;
Hao, Jiqing
;
Yang, Nong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/13
apatinib
angiogenesis
gastric adenocarcinoma
pharmacokinetics
VEGFR
VEGFR-2
Drug Degradation Caused by mce3R Mutations Confers Contezolid (MRX-I) Resistance in Mycobacterium tuberculosis
期刊论文
OAI收割
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2022, 卷号: 66, 期号: 10, 页码: 11
作者:
Pi, Rui
;
Chen, Xiaomin
;
Meng, Jian
;
Liu, Qingyun
;
Chen, Yiwang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/11/11
Mycobacterium tuberculosis
drug resistance
contezolid
Mce3R
Rv1936
degradation
drug resistance mechanisms