中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [23]
自动化研究所 [2]
海洋研究所 [1]
合肥物质科学研究院 [1]
采集方式
OAI收割 [27]
内容类型
期刊论文 [27]
发表日期
2023 [27]
学科主题
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共27条,第1-10条
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发表日期:2023
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Safety, tolerability and pharmacokinetics of forsythin in healthy subjects: a double-blinded, placebo-controlled single-dose and multiple-dose escalation and food effect study
期刊论文
OAI收割
ANNALS OF MEDICINE, 2023, 卷号: 55, 期号: 2, 页码: 9
作者:
Li, Cuiyun
;
Wu, Min
;
Zhang, Hong
;
Zhu, Xiaoxue
;
Fu, Li
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/01/16
Forsythin
pharmacokinetics
safety
tolerability
food effect
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Ginsenoside Rg3 endows liposomes with prolonged blood circulation and reduced accelerated blood clearance
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 364, 页码: 23-36
作者:
Xia, Jiaxuan
;
Chen, Chen
;
Dong, Meichen
;
Zhu, Ying
;
Wang, Anni
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/01/16
Ginsenoside Rg3
Liposomes
Polyethylene glycol
Long circulation
Accelerated blood clearance (ABC)
IgM antibody
Complement activation
Pharmacokinetic and metabolite profile of orally administered anemoside B4 in rats with an improved exposure in formulations of rectal suppository
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 315, 页码: 11
作者:
Ye, Yaqing
;
Xue, Mingzhen
;
Tian, Xiaoting
;
Gao, Hongwei
;
Hu, Pei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Anemoside B4
Pulsatilla chinensis
metabolite identification
Pharmacokinetics
Rectal suppository
A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11
作者:
Zhou, Ainan
;
Yu, Jinghua
;
Wu, Yali
;
Xue, Hao
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Monoclonal antibody
Bevacizumab
LC-MS
MS
Surrogate peptide
Pharmacokinetics
Serum
Loratadine oral bioavailability enhancement via solid dispersion loaded oro-dispersible films: Formulation, characterization and pharmacokinetics
期刊论文
OAI收割
COLLOIDS AND SURFACES B-BIOINTERFACES, 2023, 卷号: 230
作者:
Islam, Nayyer
;
Khan, Naveed Ullah
;
Razzaq, Anam
;
Menaa, Farid
;
Khan, Zaheer Ullah
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/17
Loratadine
Solid dispersion
Oro-dispersible film
Bioavailability
Urticaria
Molecular imaging-guided extracellular vesicle-based drug delivery for precise cancer management: Current status and future perspectives
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 362, 页码: 97-120
作者:
Cheng, Zhongquan
;
Shang, Jihuan
;
Wang, Huarong
;
Yu, Leyi
;
Yuan, Zhu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/16
Extracellular vesicles
Molecular imaging
Cancer
Diagnosis
Therapy
[
68
Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 11
作者:
Zhou, Ming
;
Xiang, Shijun
;
Zhao, Yajie
;
Tang, Yongxiang
;
Yang, Jinhui
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/16
PD-1/PD-L1
Immune checkpoints
PET/CT imaging
Immunotherapy
Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15
作者:
Jing, Shisuo
;
Chen, Huayuan
;
Liu, Ergang
;
Zhang, Meng
;
Shen, Huan
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2023/10/17
Inflammatory bowel disease
Quercetin
colon-targeted delivery
Pectin microsphere
Oligochitosan
Immune microenvironment
AhR-STAT3-HO-1/COX-2 signalling pathway may restrict ferroptosis and improve hMSC accumulation and efficacy in mouse liver
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2023, 页码: 17
作者:
Han, Li
;
Ma, Chenhui
;
Wu, Zhitao
;
Xu, Huiming
;
Li, Hai
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/08
aryl hydrocarbon receptor
ferroptosis
iron
ischaemia/reperfusion liver injury
liver disease
mesenchymal stem cells