中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [1036]
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OAI收割 [1036]
内容类型
期刊论文 [1027]
会议论文 [5]
学位论文 [2]
专著章节 [1]
项目 [1]
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2024 [10]
2023 [72]
2022 [86]
2021 [59]
2020 [61]
2019 [67]
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Pharmacol... [16]
Chemistry [11]
Biochemist... [6]
Oncology [4]
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浏览/检索结果:
共1036条,第1-10条
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专题:上海药物研究所
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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433
作者:
Tao, Hongru
;
Jin, Chen
;
Zhou, Liyuan
;
Deng, Zhenzhong
;
Li, Xiao
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/09
Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP)
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279
作者:
Zhou, Chenmao
;
Hao, Xinyue
;
Chen, Zhengyang
;
Zhang, Runze
;
Zhou, Qian
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/13
Speckle-type POZ protein (SPOP)
SPOP inhibitors
Clear cell renal cell carcinoma (ccRCC)
Structure-activityrelationship (SAR)
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1
H
)-one Analogues as Potent TRK Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:
Xu, Zichao
;
Peng, Xia
;
Zhang, Renjie
;
Ji, Yinchun
;
You, Mengke
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
Revisiting the Role of Valeric Acid in Manipulating Ulcerative Colitis
期刊论文
OAI收割
INFLAMMATORY BOWEL DISEASES, 2024, 页码: 12
作者:
Liu, Moting
;
Zhang, Yao
;
Liu, Jia
;
Xiang, Caigui
;
Lu, Qiukai
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/19
ulcerative colitis
macrophages
gut microbes
scfas
valeric acid
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Li, Wen-jing
;
Xie, Cheng-ying
;
Zhu, Xi
;
Tang, Jiao
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/19
SIBP-03
HER3
HER3-targeted therapy
neuregulin 1
EGFR
HER2
Unraveling the complex roles of macrophages in obese adipose tissue: an overview
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2024, 页码: 32
作者:
Peng, Chang
;
Chen, Jun
;
Wu, Rui
;
Jiang, Haowen
;
Li, Jia
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/02/19
obesity
inflammation
adipose tissue macrophages
adipose tissue homeostasis
A proteomic landscape of pharmacologic perturbations for functional relevance
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 1, 页码: 128-139
作者:
Liu, Zhiwei
;
Jiang, Shangwen
;
Hao, Bingbing
;
Xie, Shuyu
;
Liu, Yingluo
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/04/09
Proteomics
Drug
Perturbation
Drug target
Drug combination
Role of F-box proteins in human upper gastrointestinal tumors
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2024, 卷号: 1879, 期号: 1, 页码: 16
作者:
Zhang, Che
;
Pan, Guangzhao
;
Qin, Jiang-Jiang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/02/27
F-box protein
Upper gastrointestinal cancer
E3 ubiquitin ligase
Ubiquitin