机构

• 上海药物研究所 [9]
• 上海生物化学与细胞生... [1]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2018 [11]

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2018     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文  OAI收割 SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873 作者:  Li, R.;  Du, Y.;  Shen, J.   |  收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 BTK inhibitors  B-cell malignancies  molecule docking  3D-QSAR  CoMFA  CoMSIA   Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9085-9104 作者:  Wang, Yuming;  Li, Lijun;  Fan, Jun;  Dai, Yang;  Jiang, Alan   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 6, 页码: 1048-1063 作者:  Zhong, Chen-chun;  Chen, Feng;  Yang, Jun-ling;  Jia, Wei-wei;  Li, Li   |  收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 anlotinib  tyrosine kinase inhibitor  absorption  distribution  metabolism  excretion  pharmacokinetics   Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86 作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin   |  收藏  |  浏览/下载：146/0  |  提交时间：2019/01/08 Heat shock protein 90 (Hsp90)  Tyrosine kinase ALK  Dual inhibitor  Drug resistance  Antiproliferative activity   Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFR alpha kinase inhibitor for PDGFR alpha driving chronic eosinophilic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 期号: 无, 页码: 366-384 作者:  Wang, Qiang;  Liu, Feiyang;  Qi, Shuang;  Qi, Ziping;  Yan, Xiao-E.   |  收藏  |  浏览/下载：62/0  |  提交时间：2019/06/10 PDGFR kinase  Type II inhibitor  Kinase inhibitor  CEL   YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo 期刊论文  OAI收割 CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439 作者:  Zhang, Zhang;  Zou, Jian;  Yu, Lei;  Luo, Jinfeng;  Li, Yan   |  收藏  |  浏览/下载：70/0  |  提交时间：2019/01/08 EGFR inhibitor  lung cancer  pharmacokinetic  selectively  T790M mutation   Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 期号: 4, 页码: 751-762 作者:  Ai, Jing;  Chen, Yi;  Peng, Xia;  Ji, Yinchun;  Xi, Yong   |  收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 243-250 作者:  Jiang, Xi-fei;  Dai, Yang;  Peng, Xia;  Shen, Yan-yan;  Su, Yi   |  收藏  |  浏览/下载：53/0  |  提交时间：2019/01/08 human cancer  anticancer drug  SOMCL-085  receptor tyrosine kinase  FGFR  xenograft nude mouse model   Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death 期刊论文  OAI收割 CELL DEATH & DISEASE, 2018, 卷号: 9 作者:  Ouchida, Amanda Tomie;  Li, Yingbo;  Geng, Jiefei;  Najafov, Ayaz;  Ofengeim, Dimitry   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Targeting HER2 Aberrations in Non-Small Cell Lung Cancer with Osimertinib 期刊论文  OAI收割 CLINICAL CANCER RESEARCH, 2018, 卷号: 24, 期号: 11, 页码: 2594-2604 作者:  Liu, Shengwu;  Hai, Josephine;  Wang, Xiaoen;  Quinn, Max M.;  Gao, Peng   |  收藏  |  浏览/下载：81/0  |  提交时间：2019/04/28 Receptor Tyrosine Kinase  Phase-ii Trial  Bromodomain Inhibition  Combination Therapy  Acquired-resistance  Domain Mutations  Bet Bromodomains  Breast-cancer  Egfr  Mutant