机构

• 合肥物质科学研究院 [7]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2022 [2]
• 2021 [1]
• 2018 [1]
• 2017 [1]
• 2016 [2]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 限定条件 专题：合肥物质科学研究院    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China 期刊论文  OAI收割 THORACIC CANCER, 2022 作者:  Xu, Chunwei;  Si, Lu;  Wang, Wenxian;  Li, Ziming;  Song, Zhengbo   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/12/22 fusion  precision medicine  solid tumor  targeted therapy  tyrosine receptor kinase   CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022 作者:  Cao, Jiang-yan;  Qi, Shuang;  Wu, Hong;  Wang, Ao-li;  Liu, Qing-wang   |  收藏  |  浏览/下载：53/0  |  提交时间：2022/03/28 HER2  breast cancers  gastric cancers  irreversible inhibitor  drug resistance   Liquid chromatography-mass spectrometry based metabolic characterization of pleural effusion in patients with acquired EGFR-TKI resistance 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 202 作者:  Li, Na;  Mao, Weimin;  Gao, Yun;  Wang, Ding;  Song, Zhengbo   |  收藏  |  浏览/下载：78/0  |  提交时间：2021/08/31 Lung cancer  EGFR-TKI  Resistance  Pleural effusion  Metabolomics  Biomarker   Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFR alpha kinase inhibitor for PDGFR alpha driving chronic eosinophilic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 期号: 无, 页码: 366-384 作者:  Wang, Qiang;  Liu, Feiyang;  Qi, Shuang;  Qi, Ziping;  Yan, Xiao-E.   |  收藏  |  浏览/下载：62/0  |  提交时间：2019/06/10 PDGFR kinase  Type II inhibitor  Kinase inhibitor  CEL   Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode 期刊论文  OAI收割 ONCOTARGET, 2017, 卷号: 8, 期号: 11, 页码: 18359-18372 作者:  Hu, Chen;  Wang, Aoli;  Wu, Hong;  Qi, Ziping;  Li, Xixiang   |  收藏  |  浏览/下载：44/0  |  提交时间：2018/07/04 Egfr  Egfrt790m  Nsclc  Kinase Inhibitors  Drug Resistance   Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation 期刊论文  OAI收割 ONCOTARGET, 2016, 卷号: 7, 期号: 43, 页码: 69760-69769 作者:  Wang, Aoli;  Yan, Xiao-E;  Wu, Hong;  Wang, Wenchao;  Hu, Chen 收藏  |  浏览/下载：78/0  |  提交时间：2017/11/21 Ibrutinib  Egfr Kinase  Dfg-in/c-helix-out  Inactive Conformation  Nsclc   Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 5, 页码: 1984-2004 作者:  Liang, Xiaofei;  Liu, Xiaochuan;  Wang, Beilei;  Zou, Fengming;  Wang, Aoli 收藏  |  浏览/下载：44/0  |  提交时间：2017/11/06