中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [50]
采集方式
OAI收割 [50]
内容类型
期刊论文 [48]
会议论文 [2]
发表日期
2024 [1]
2023 [4]
2022 [4]
2021 [3]
2020 [7]
2019 [2]
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专题:上海药物研究所
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Intelligent design and construction of novel APN-based theranostic probe driven by advanced computational methods
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 2, 页码: 6
作者:
Zhu, Yingli
;
Qian, Jie
;
Yu, Kunqian
;
Hou, Jing
;
Ma, Yeshuo
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/01/26
Theranostic probe
Artificial intelligence
Conformational restriction
Fluorescence restoration
Design strategy
Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287
作者:
Hu, Linghao
;
Li, Huiyun
;
Qin, Junlin
;
Yang, Dan
;
Liu, Jieming
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/02/27
Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925
作者:
Zhou, Wei
;
Fang, Peng
;
Yu, Dongan
;
Ren, Hongyuan
;
You, Meng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial
期刊论文
OAI收割
JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655
作者:
Liu, Songqiao
;
Yao, Chen
;
Xie, Jianfeng
;
Liu, Hong
;
Wang, Hongliang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/27
Redox-neutral rhodium(iii)-catalyzed divergent synthesis of tetrasubstituted 1,3-enynes and alkynylated benzofurans
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 1, 页码: 147-152
作者:
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Convergent Synthesis and Anti-Pancreatic Cancer Cell Growth Activity of a Highly Branched Heptadecasaccharide from Carthamus tinctorius
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 9
作者:
Hu, Chaoyu
;
Wu, Shengjie
;
He, Fei
;
Cai, Deqin
;
Xu, Zhuojia
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/08/16
Antitumor Agents
Carbohydrates
Glycosylation
Oligosaccharides
Total Synthesis
Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3
期刊论文
OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 11
作者:
Shao, Zhehua
;
Tan, Yangxia
;
Shen, Qingya
;
Hou, Li
;
Yao, Bingpeng
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/08/16
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 17
作者:
Jiao, Ting-ying
;
Ma, Yuan-di
;
Guo, Xiao-zhen
;
Ye, Yun-fei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/06/15
bile acids
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
drug target
Farnesoid X receptor
G protein-coupled bile acid receptor
Antidepressant-like effects of cinnamamide derivative M2 via D-2 receptors in the mouse medial prefrontal cortex
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 9
作者:
Che, Yan-xin
;
Jin, Xiao-yan
;
Xiao, Rong-hua
;
Zhang, Ming
;
Ma, Xiao-hui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/06/15
depression
D-2 receptor
medial prefrontal cortex
pyramidal neurons
mTOR
TrkB
Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2021, 页码: 24
作者:
Shao, Zhehua
;
Shen, Qingya
;
Yao, Bingpeng
;
Mao, Chunyou
;
Chen, Li-Nan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/06/15