中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2023 [1]
2022 [2]
2021 [2]
2020 [3]
2019 [1]
2018 [1]
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专题:上海药物研究所
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Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15
作者:
Jing, Shisuo
;
Chen, Huayuan
;
Liu, Ergang
;
Zhang, Meng
;
Shen, Huan
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2023/10/17
Inflammatory bowel disease
Quercetin
colon-targeted delivery
Pectin microsphere
Oligochitosan
Immune microenvironment
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540
作者:
Xie, Xiong
;
Zheng, Yu-Gui
;
Chen, Huan
;
Li, Jian
;
Luo, Rong-Hua
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Absorption, distribution, metabolism, and excretion of [C-14]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 页码: 12
作者:
Li, Xin-mei
;
Zheng, Yuan-dong
;
Zhang, Yi-fan
;
Huan, Xia-juan
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13
[C-14]Mefuparib
Mefuparib (CVL218)
Blood-brain barrier
Mass balance
Tissue distribution
GastroPlus simulation
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
OAI收割
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:
Zhang, Ning
;
Tian, Yu-Nan
;
Zhou, Li-Na
;
Li, Meng-Zhu
;
Chen, Hua-Dong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
OAI收割
Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1
作者:
Ning Zhang
;
Yu-Nan Tian
;
Li-Na Zhou
;
Meng-Zhu Li
;
Hua-Dong Chen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/12/01
Chemical constituents from the South China sea soft coral Sinularia humilis
期刊论文
OAI收割
NATURAL PRODUCT RESEARCH, 2020, 页码: 7
作者:
Li, Jie
;
Huan, Xia-Juan
;
Wu, Meng-Jun
;
Chen, Zi-Hui
;
Chen, Bao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
Soft coral
Sinularia humilis
diterpenoids
capnosane
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
OAI收割
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
Two new hydroperoxy steroids from the South China Sea gorgonian Rumphella sp.
期刊论文
OAI收割
STEROIDS, 2020, 卷号: 155, 页码: 4
作者:
Yin, Fang-Zhou
;
Yang, Min
;
Li, Song-Wei
;
Wu, Meng-Jun
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Gorgonian
Rumphella sp.
Hydroperoxy steroids
Cytotoxicities
Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 18, 页码: 8642-8663
作者:
Hu, Jianping
;
Tian, Chang-Qing
;
Damaneh, Mohammadali Soleimani
;
Li, Yanlian
;
Cao, Danyan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636
作者:
Peng, Panfeng
;
Chen, Huan
;
Zhu, Ya
;
Wang, Zhilong
;
Li, Jian
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08