机构

• 上海药物研究所 [89]

采集方式

• OAI收割 [89]

内容类型

• 期刊论文 [88]
• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [6]
• 2022 [10]
• 2021 [12]
• 2020 [8]
• 2019 [10]
• 更多

学科主题

筛选

浏览/检索结果: 共89条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of Epimedium and Psoraleae Fructus herb pair after oral administration 期刊论文  OAI收割 JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17 作者:  Wang, Linwei;  Yin, Xiaoying;  Liu, Huan;  Wang, Yangyang;  Li, Zhixiong   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/02/27 compatibility behaviors  Epimedium  LC-MS/MS  pharmacokinetics  Psoraleae Fructus   Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells 期刊论文  OAI收割 LIFE SCIENCES, 2023, 卷号: 332, 页码: 10 作者:  Su, Ai-Ling;  Tian, Chang-Qing;  Ou, Ying-Jie;  Bao, Xu-Bin;  Huan, Xia-Juan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 CD73  Proteasome inhibitors  ERK  NSCLC   Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9 作者:  Li, Hua-ying;  Chen, Yi-li;  Deng, Xiang-nan;  Li, Huan-huan;  Tan, Jie   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 cancer immunotherapy  B7-H3  PD-L1  bispecific antibodies  VHH  antibody-dependent cell-mediated cytotoxicity (ADCC)   Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   E3 ligase ligand optimization of Clinical PROTACs 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2023, 卷号: 11, 页码: 15 作者:  Jiang, Hanrui;  Xiong, Huan;  Gu, Shuang-Xi   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/10 PROTACs  E3 ubiquitin ligase ligand  structure optimization  clinical trials  CRBN   Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221 作者:  He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/05/22 TPN171  14CTPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   TRPV4 is not the molecular sensor for bacterial lipopolysaccharides-induced calcium signaling 期刊论文  OAI收割 CELLULAR IMMUNOLOGY, 2023, 卷号: 383, 页码: 8 作者:  Wang, Yuhui;  Hao, Yanping;  Jin, Jinhua;  Yi, Zhihua;  Liu, Yifei   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 TRPV4  LPS  Calcium influx  Whole cell current  Pain  Inflammation   Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540 作者:  Xie, Xiong;  Zheng, Yu-Gui;  Chen, Huan;  Li, Jian;  Luo, Rong-Hua   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/04/10 Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells 期刊论文  OAI收割 MOLECULAR CANCER RESEARCH, 2022, 卷号: 20, 期号: 12, 页码: 1785-1798 作者:  Sun, Lin;  Wu, Qian;  Huan, Xia-Juan;  Tian, Chang-Qing;  Wang, Ying-Qing   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy 期刊论文  OAI收割 NEOPLASIA, 2022, 卷号: 32, 页码: 12 作者:  Zhou, Li-Na;  Xiong, Chaodong;  Cheng, Yong-Jun;  Song, Shan-Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 SOMCL-19-133  NAE inhibitor  MLN4924  NEDD8  Oral administration