机构

• 上海药物研究所 [13]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2023 [2]
• 2022 [3]
• 2021 [1]
• 2020 [2]
• 2017 [5]

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Deletion of Schizophrenia Susceptibility Gene Ulk4 Leads to Abnormal Cognitive Behaviors via Akt-GSK-3 Signaling Pathway in Mice 期刊论文  OAI收割 SCHIZOPHRENIA BULLETIN, 2022, 页码: 10 作者:  Hu, Ling;  Zhou, Bing-Yao;  Yang, Cui-Ping;  Lu, Da-Yun;  Tao, Yun-Chao   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/06/15 Unc-51-like kinase 4  schizophrenia  sensorimotor gating  Akt  GSK-3  cerebral cortex   Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody 期刊论文  OAI收割 SCIENCE, 2022, 卷号: 375, 期号: 6584, 页码: 1048-+ 作者:  Yin, Wanchao;  Xu, Youwei;  Xu, Peiyu;  Cao, Xiaodan;  Wu, Canrong   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15 Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity 期刊论文  OAI收割 CHINESE JOURNAL OF NATURAL MEDICINES, 2022, 卷号: 20, 期号: 2, 页码: 139-147 作者:  Liu Yu;  You Yun-Xia;  Rao Li;  He Qian;  Su Yu   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/06/15 Illicium micranthum  Geranyl phenyl ethers  Spectroscopic data  Anti-HBV activity   Iridoid Constituents of Viburnum brachybotryum 期刊论文  OAI收割 JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 7, 页码: 1915-1923 作者:  Rao, Li;  Li, Yao;  He, Qian;  Liu, Yu;  Su, Yu   |  收藏  |  浏览/下载：22/0  |  提交时间：2021/11/04 Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文  OAI收割 SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+ 作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya   |  收藏  |  浏览/下载：33/0  |  提交时间：2020/12/24 Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 2, 页码: 804-815 作者:  Zhang, Shu-Wei;  Gong, Chao-Jun;  Su, Ming-Bo;  Chen, Fei;  He, Ting   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1038-1047 作者:  Yang, Zhong-min;  Liao, Xue-mei;  Chen, Yi;  Shen, Yan-yan;  Yang, Xin-ying   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 homologous recombination repair defects  breast cancer  ovarian cancer  TALEN  combined biomarker  simmiparib  olaparib