机构

• 上海药物研究所 [207]

采集方式

• OAI收割 [207]

内容类型

• 期刊论文 [202]
• 会议论文 [5]

发表日期

• 2024 [2]
• 2023 [13]
• 2022 [10]
• 2021 [17]
• 2020 [11]
• 2019 [12]
• 更多

学科主题

• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共207条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Ent-labdane-type diterpene glycosides obtained from Rubus chingii Hu and their inhibitory effects on PDE5A activity 期刊论文  OAI收割 FITOTERAPIA, 2024, 卷号: 173, 页码: 14 作者:  Yu, Jun-dong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 diterpene glycosides  Rubus Chingii Hu  PDE5A inhibitory activity  ent-labdane   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model 期刊论文  OAI收割 CELL, 2023, 卷号: 186, 期号: 24, 页码: 5394-+ 作者:  Chen, Yefei;  Hong, Zexuan;  Wang, Jingyi;  Liu, Kunlin;  Liu, Jing   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26 Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9 作者:  He, Wen-Zhuo;  Huang, Yu-Hua;  Hu, Wan-Ming;  Wang, Fang;  Xu, Yu-Xia   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/11 Epstein-Barr virus  Intrahepatic cholangiocarcinoma  Programmed cell death protein 1  Immunotherapy   Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18 作者:  Zhong, Jing;  He, Xiaofang;  Gao, Xinxin;  Liu, Qiaohong;  Zhao, Yu   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/08 ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571 作者:  Zhang, Yanqiong;  Li, Xin;  Shi, Yulong;  Chen, Tong;  Xu, Zhijian   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 Traditional Chinese medicine  Database  Target identification  Network visualization  New drug research and development  Molecular mechanism  Quality marker  Drug repurposing   Late-Stage Functionalization for the Divergent Synthesis of Podophyllotoxin Derivatives by Rhodium Catalysis 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 10 作者:  Zhao, Yue;  Shen, Yangpeng;  He, Jian;  Li, Jing;  Zhou, Shengbin   |  收藏  |  浏览/下载：138/0  |  提交时间：2023/10/17 anticancer  C-H bond activation  divergent synthesis  podophyllotoxin  late-stage functionalization   A patent review of PRMT5 inhibitors to treat cancer (2018-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2023, 页码: 28 作者:  Gao, Jing;  Yang, Jie;  Xue, Shengyu;  Ding, Hong;  Lin, Hua   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 PRMT5  inhibitor  epigenetic target  cancer treatment  combined treatment