机构

• 上海药物研究所 [44]

采集方式

• OAI收割 [44]

内容类型

• 期刊论文 [43]
• 会议论文 [1]

发表日期

• 2023 [4]
• 2022 [3]
• 2021 [8]
• 2020 [4]
• 2019 [2]
• 2018 [2]
• 更多

学科主题

• Pharmacolo... [1]

筛选

浏览/检索结果: 共44条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Synthesis, cytotoxicity, and pharmacokinetic evaluations of niclosamide analogs for anti-SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 11 作者:  Li, Rui;  Zhang, Zherui;  Huang, Shuhong;  Peng, Ke;  Jiang, Hualiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 SARS-CoV-2  Niclosamide analogs  Cytotoxicity  Pharmacokinetic  SKP2 inhibition   Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors 期刊论文  OAI收割 NATURE CHEMISTRY, 2023, 页码: 18 作者:  Guo, An-Di;  Yan, Ke-Nian;  Hu, Hao;  Zhai, Linhui;  Hu, Teng-Fei   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 18, 页码: 11 作者:  Xu, Haiyu;  Li, Shufen;  Liu, Jiayuan;  Cheng, Jinlong;  Kang, Liping   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 COVID-19  traditional Chinese medicine  TCMT-NDRD  antivirus  anti-inflammation   Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10 作者:  Song, Jia;  Yang, Rui-rui;  Chang, Jie;  Liu, Ya-dan;  Lu, Cheng-hao   |  收藏  |  浏览/下载：48/0  |  提交时间：2022/11/11 cyclic GMP-AMP synthase  covalent inhibitor  inflammatory bowel disease  high-throughput screening   Recent progress in fragment-based drug discovery facilitated by NMR spectroscopy 期刊论文  OAI收割 Magnetic Resonance Letters, 2022, 卷号: 2, 期号: 2, 页码: 107-118 作者:  Wang, Lei;  Gao, Jia;  Ma, Rongsheng;  Liu, Yaqian;  Liu, Mingqing   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/14 Fragment-based lead/drug discovery  NMR spectroscopy  Protein-ligand interaction  Complex structure  Hit-to-lead evolution   Dietary alcohol exacerbates the hepatotoxicity induced by pyrrolizidine alkaloids: Hazard from food contamination 期刊论文  OAI收割 JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 424, 页码: 12 作者:  He, Yisheng;  Long, Yun;  Zhang, Chunyuan;  Ma, Jiang;  Ke, Changqiang   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/06/15 food contamination  pyrrolizidine alkaloids  alcohol  dietary exposure  mead   Rearranged Diels-Alder Adducts and Prenylated Flavonoids as Potential PTP1B Inhibitors from Morus nigra 期刊论文  OAI收割 JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 8, 页码: 2303-2311 作者:  Qu, Ke-Jun;  Wang, Bin;  Jiang, Chang-Sheng;  Xie, Bao-Gang;  Liu, Ai-Hong   |  收藏  |  浏览/下载：29/0  |  提交时间：2021/11/04 Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya   |  收藏  |  浏览/下载：94/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators   Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12 作者:  Su, Haixia;  Yao, Sheng;  Zhao, Wenfeng;  Zhang, Yumin;  Liu, Jia   |  收藏  |  浏览/下载：57/0  |  提交时间：2021/08/17