中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [38]
采集方式
OAI收割 [38]
内容类型
期刊论文 [36]
会议论文 [2]
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2023 [3]
2022 [4]
2021 [3]
2020 [1]
2017 [2]
2016 [1]
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浏览/检索结果:
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专题:上海药物研究所
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Building Block Extractor: An MS/MS Data Mining Tool for Targeted Discovery of Natural Products with Specified Features
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2023, 页码: 8
作者:
Zhu, Dafu
;
Yuan, Jie
;
Yue, Quanqi
;
Zhao, Yinggong
;
Yu, Shan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
Identification of lignans as ATP citrate lyase (ACLY) inhibitors from the roots of Pouzolzia zeylanica
期刊论文
OAI收割
NATURAL PRODUCT RESEARCH, 2023, 页码: 8
作者:
Li, Jin-Long
;
Jiang, Jia-Yi
;
Gu, Shan-Shan
;
Zhang, Lei
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Pouzolzia zeylanica
lignans
ATP citrate lyase (ACLY) inhibitors
Current approaches of nanomedicines in the market and various stage of clinical translation
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 7, 页码: 3028-3048
作者:
Shan, Xiaoting
;
Gong, Xiang
;
Li, Jie
;
Wen, Jingyuan
;
Li, Yaping
  |  
收藏
  |  
浏览/下载:135/0
  |  
提交时间:2024/03/21
Nanomedicines
Nanoparticles
Liposomes
Vaccines
Marketed products
Clinical translations
Disease-driven design
Quality by design
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 9
作者:
Qian, Hong-jie
;
Wang, Yu
;
Zhang, Meng-qi
;
Xie, Yuan-chao
;
Wu, Qing-qing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
VV116
nucleoside analog
SARS-CoV-2
safety
pharmacokinetics
healthy subjects
Poly(maleic anhydride-alt-1-octadecene)-based bioadhesive nanovehicles improve oral bioavailability of poor water-soluble gefitinib
期刊论文
OAI收割
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2022, 卷号: 48, 期号: 3, 页码: 109-116
作者:
Wang, Guanru
;
Xie, Yaru
;
Qian, Xindi
;
Zhang, Xinyue
;
Shan, Yanqiang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/21
Gefitinib
nanovehicle
oral bioavailability
poorly water soluble drugs
bioadhesive
Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR(T790M/C797S) Mutants
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 7
作者:
Li, Shan
;
Zhang, Tao
;
Zhu, Su-Jie
;
Lei, Chong
;
Lai, Mengzhen
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/06/15
Epidermal Growth Factor Receptor (EGFR)
Resistant Mutation
C797S
Antitumor
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Discovery of New alpha-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 9
作者:
Liu, Shan-Kui
;
Hao, Haifang
;
Bian, Yuan
;
Ge, Yong-Xi
;
Lu, Shengyuan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
α
-glycosidase
virtual screening
cytotoxicity
type 2 diabetes
molecular docking
Suppression of Th17 cell differentiation via sphingosine-1-phosphate receptor 2 by cinnamaldehyde can ameliorate ulcerative colitis
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 134, 页码: 111116
作者:
Qu, Shu-lan
;
Chen, Long
;
Wen, Xue-shan
;
Zuo, Jian-ping
;
Wang, Xiao-yu
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/21
Cinnamaldehyde
Ulcerative colitis
Th17 cells
S1P2
LncRNA