中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
采集方式
OAI收割 [18]
内容类型
期刊论文 [18]
发表日期
2023 [1]
2021 [1]
2020 [1]
2019 [3]
2018 [2]
2017 [1]
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浏览/检索结果:
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专题:上海药物研究所
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DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Wu, Chun-mei
;
Mao, Jia-wen
;
Zhu, Jin-zhi
;
Xie, Can-can
;
Yao, Jia-ying
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
dry eye disease
DZ2002
corneal angiogenesis
immunomodulatory function
NF-kappa B
ophthalmic therapy
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis
期刊论文
OAI收割
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:
Zhang, Zi-jia
;
Wu, Wen-yong
;
Hou, Jin-jun
;
Zhang, Lin-lin
;
Li, Fei-fei
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
Lung-toxin Dispelling Formula No. 1
COVID-19
3C-like protease
Network pharmacology
Molecular docking
Meridian tropism
Polycyclic polyprenylated acylphloroglucinols from Hypericum choisianum
期刊论文
OAI收割
NATURAL PRODUCT RESEARCH, 2019, 页码: 8
作者:
Zhang, Hai-Bo
;
Zhang, Xu
;
Jiang, Kun
;
Qu, Shi-Jin
;
Meng, Ling-Hua
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Hypericum choisianum
PPAPs
Hyperichoisins A - C
NMR analysis
The dynamic conformational landscape of the protein methyltransferase SETD8
期刊论文
OAI收割
ELIFE, 2019, 卷号: 8, 页码: 76
作者:
Chen, Shi
;
Wiewiora, Rafal P.
;
Meng, Fanwang
;
Babault, Nicolas
;
Ma, Anqi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Triterpenoids, megastigmanes and hydroxycinnamic acid derivatives from Anisomeles indica
期刊论文
OAI收割
Natural product research, 2019, 卷号: 33, 期号: 1, 页码: 41-46
作者:
Liu, Quan-Wen
;
Chen, Cai-Hua
;
Wang, Xiao-Feng
;
Jiang, Kun
;
Qu, Shi-Jin
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/01/08
2alpha,3alpha,19alpha-trihydroxyurs-12,20(30)-dien-28-oic acid
Lamiaceae
hydroxycinnamic acids
megastigmanes
triterpenoids
Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298
作者:
Zhu, Kongkai
;
Tao, Hongrui
;
Song, Jia-Li
;
Jin, Lu
;
Zhang, Yuanyuan
  |  
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Arginine methylation
Virtual screening
Molecular docking
Molecular dynamics simulation
The HNF1 alpha-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1
期刊论文
OAI收割
MOLECULAR CANCER, 2018, 卷号: 17
作者:
Ding, Chen-Hong
;
Yin, Chuan
;
Chen, Shi-Jie
;
Wen, Liang-Zhi
;
Ding, Kai
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
HNF1 alpha
HNF1A-AS1
Hepatocellular carcinoma
SHP-1
phosphatase activity
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials
期刊论文
OAI收割
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:
Yuan, Bo
;
Ye, Na
;
Song, Shan-Shan
;
Wang, Yu-Ting
;
Song, Zilan
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
Homologous recombination repair defects
Olaparib
Growth inhibition
Patient-derived xenografts
Pharmacokinetics
Venenum Bufonis induces rat neuroinflammation by activiating NF-kappa B pathway and attenuation of BDNF
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2016, 卷号: 186, 页码: 103-110
作者:
Bi, Qi-rui
;
Hou, Jin-jun
;
Qi, Peng
;
Ma, Chun-hua
;
Shen, Yao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Brain-derived neurotrophic factor (BDNF)
Inflammation
Neurotoxicity NF
NF- < kappa > B pathway
Venenum Bufonis