机构

• 上海药物研究所 [163]

采集方式

• OAI收割 [163]

内容类型

• 期刊论文 [163]

发表日期

• 2024 [1]
• 2023 [8]
• 2022 [9]
• 2021 [10]
• 2020 [13]
• 2019 [8]
• 更多

学科主题

• Biochemist... [1]

筛选

浏览/检索结果: 共163条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906 作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/04/09 Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter 期刊论文  OAI收割 BMC CANCER, 2023, 卷号: 23, 期号: 1, 页码: 20 作者:  Ren, Ganglin;  Li, Hongyan;  Hong, Dan;  Hu, Fangyu   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 LINC00955  Colorectal cancer  Cell cycle  CDK2  PHIP  Sp1   Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial 期刊论文  OAI收割 JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655 作者:  Liu, Songqiao;  Yao, Chen;  Xie, Jianfeng;  Liu, Hong;  Wang, Hongliang   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region 期刊论文  OAI收割 JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942 作者:  Jiang, Hao;  Zu, Shijia;  Lu, Yu;  Sun, Zhongya;  Adeerjiang, Akejiang   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 Small GTPases  Crystal structures of RhoA  Dynamics of switch II  Molecular dynamics simulations  Allosteric pocket   Identification of lignans as ATP citrate lyase (ACLY) inhibitors from the roots of Pouzolzia zeylanica 期刊论文  OAI收割 NATURAL PRODUCT RESEARCH, 2023, 页码: 8 作者:  Li, Jin-Long;  Jiang, Jia-Yi;  Gu, Shan-Shan;  Zhang, Lei;  Sun, Yan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Pouzolzia zeylanica  lignans  ATP citrate lyase (ACLY) inhibitors   Rh-Catalyzed C-H Activation/Annulation of Enaminones and Cyclic 1,3-Dicarbonyl Compounds: An Access to Isocoumarins 期刊论文  OAI收割 JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 88, 期号: 9, 页码: 5348-5358 作者:  Wang, Qian;  Li, Ying;  Sun, Jina;  Chen, Shiyu;  Li, Hui   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis 期刊论文  OAI收割 Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 4, 页码: 1857-1873 作者:  Dong, Ying;  Hu, Hao;  Zhang, Xuan;  Zhang, Yunkai;  Sun, Xin   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/27 Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms 期刊论文  OAI收割 CHEMICAL COMMUNICATIONS, 2022, 页码: 4 作者:  Li, Jian;  Sun, Jina;  Zhang, Xianglei;  Zhang, Ruxue;  Wang, Qian   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/04/10