中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [45]
采集方式
OAI收割 [45]
内容类型
期刊论文 [45]
发表日期
2023 [7]
2022 [7]
2019 [3]
2018 [4]
2017 [6]
2016 [5]
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专题:上海药物研究所
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Inhibiting Endothelial Cell-Mediated T Lymphocyte Apoptosis with Integrin-Targeting Peptide-Drug Conjugate Filaments for Chemoimmunotherapy of Triple-Negative Breast Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2023, 页码: 12
作者:
Cai, Ying
;
Zhu, Binyu
;
Shan, Xiaoting
;
Zhou, Lingli
;
Sun, Xujie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
Fas ligand
immunotherapy
peptide-drug conjugate
triple-negative breast cancer
tumor-associated endothelial cells
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
STING agonist-boosted mRNA immunization via intelligent design of nanovaccines for enhancing cancer immunotherapy
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 10, 页码: 16
作者:
Zhou, Lei
;
Yi, Wenzhe
;
Zhang, Zehong
;
Shan, Xiaoting
;
Zhao, Zitong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
vaccine
mRNA
STING
cancer immunotherapy
nanoparticles
Identification of lignans as ATP citrate lyase (ACLY) inhibitors from the roots of Pouzolzia zeylanica
期刊论文
OAI收割
NATURAL PRODUCT RESEARCH, 2023, 页码: 8
作者:
Li, Jin-Long
;
Jiang, Jia-Yi
;
Gu, Shan-Shan
;
Zhang, Lei
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Pouzolzia zeylanica
lignans
ATP citrate lyase (ACLY) inhibitors
PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1
期刊论文
OAI收割
MedComm, 2023, 卷号: 4, 期号: 2, 页码: e245
作者:
Xie, Fei
;
Zhang, Han
;
Zhu, Kongkai
;
Jiang, Cheng-Shi
;
Zhang, Xiaoya
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/26
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 1, 页码: 157-173
作者:
Sun, Mingming
;
Li, Leilei
;
Niu, Yujia
;
Wang, Yingzhi
;
Yan, Qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/27
Lung cancer
Metabolic reprogramming
Post-translational modification
PRMT6
Pentose phosphate pathway flux
Glycolysis
6-Phospho-gluconate dehydrogenase
a-enolase
ENO1
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 19
作者:
Hu, Cheng-Long
;
Chen, Bing-Yi
;
Li, Zijuan
;
Yang, Tianbiao
;
Xu, Chun-Hui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13
PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 10, 页码: 15
作者:
Yu, Xiaolu
;
Long, Yiru
;
Chen, Binfan
;
Tong, Yongliang
;
Shan, Mengwen
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/13
PD-L1
TLR7
nanobody-drug-conjugate
cancer immunotherapy
Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV-2 papain-like protease
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2022, 卷号: 54, 期号: 8, 页码: 1133-1139
作者:
Zou, Zhihui
;
Shan, Huizhuang
;
Sun, Demeng
;
Xia, Li
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/11/11
COVID-19
SARS-CoV-2
PLpro
Parthenolide
deISGylation