机构

• 上海药物研究所 [399]

采集方式

• OAI收割 [399]

内容类型

• 期刊论文 [391]
• 会议论文 [8]

发表日期

• 2024 [6]
• 2023 [33]
• 2022 [19]
• 2021 [27]
• 2020 [35]
• 2019 [32]
• 更多

学科主题

• Pharmacolo... [5]
• Chemistry [3]
• Biochemist... [2]
• Neuroscien... [1]
• Plant Scie... [1]
• Virology [1]
• 更多

筛选

浏览/检索结果: 共399条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Probing the dynamic thermodynamic resolution and biological activity of Cu(II) and Pd(II) complexes with Schiff base ligand derived from proline 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 4, 页码: 7 作者:  Yu, Tao;  Soloshonok, Vadim A.;  Xiao, Zhekai;  Liu, Hong;  Wang, Jiang   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/04/09 Schiff bases  Biological activity  Tailor-made amino acids  Asymmetric synthesis  Chiral tridentate ligands  Square-planar Cu(II)-complexes  Square-planar Pd(II)-complexes   DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser56 to diminish pancreatic β cell function upon overnutrition 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16 作者:  Lu, Yuting;  Xu, Junyu;  Li, Yufeng;  Wang, Ruoran;  Dai, Chengqiu   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/13 Supramolecular Nano-Grid Platform to Load and Deliver Liposomes and Exosomes 期刊论文  OAI收割 SMALL STRUCTURES, 2024, 页码: 10 作者:  Li, Jing;  Ma, Wuzhen;  Ren, Xiaohong;  Guo, Tao;  Yang, Boyang   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/27 boronated organic framework  exosomes  liposomes  nano-grid particles  stimuli-responsive   Revisiting the Role of Valeric Acid in Manipulating Ulcerative Colitis 期刊论文  OAI收割 INFLAMMATORY BOWEL DISEASES, 2024, 页码: 12 作者:  Liu, Moting;  Zhang, Yao;  Liu, Jia;  Xiang, Caigui;  Lu, Qiukai   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/02/19 ulcerative colitis  macrophages  gut microbes  scfas  valeric acid   Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 17 作者:  Pu, Congying;  Li, Yize;  Fu, Yixian;  Yan, Yiyang;  Tao, Siyao   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/02/27 AIM2 inflammasome  chemotherapy  gut microbiome  ileal epithelial cells  immune checkpoint blockade  lactobacillus  segmented filamentous bacterium   Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Deng, Minjie;  Gao, Yue   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/19 Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21 作者:  Wang, Jingyi;  Lin, Jianbang;  Chen, Yefei;  Liu, Jing;  Zheng, Qiongping   |  收藏  |  浏览/下载：34/0  |  提交时间：2024/01/16 Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5 作者:  Lian, Xuanmin;  Gao, Yue;  Li, Xuemei;  Wang, Peipei;  Tong, Lexian   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/11 2-aminopyrimidine  FLT3 inhibitors  MV4-11  FLT3 mutations