中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [336]
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OAI收割 [336]
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期刊论文 [330]
会议论文 [6]
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2024 [5]
2023 [16]
2022 [25]
2021 [29]
2020 [16]
2019 [20]
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Biochemis... [13]
Pharmacolo... [5]
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浏览/检索结果:
共336条,第1-10条
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专题:上海药物研究所
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7-Dehydrocholesterol dictates ferroptosis sensitivity
期刊论文
OAI收割
NATURE, 2024, 卷号: 626, 期号: 7998, 页码: 29
作者:
Li, Yaxu
;
Ran, Qiao
;
Duan, Qiuhui
;
Jin, Jiali
;
Wang, Yanjin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Chen, Xuetao
;
Wu, Tingting
;
Du, Zhiyan
;
Kang, Wenjing
;
Xu, Rujun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/02/27
BET
BD1
Bromodomain
Brain-permeable
Multiple sclerosis
Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:
Yang, Wenjiao
;
Gong, Xudong
;
Sun, Haiguo
;
Wu, Chunhui
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/06
CB2R agonist
5-HT1AR agonist
CB1R antagonist
Antidepressant
Anxiolytic
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
Unraveling the complex roles of macrophages in obese adipose tissue: an overview
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2024, 页码: 32
作者:
Peng, Chang
;
Chen, Jun
;
Wu, Rui
;
Jiang, Haowen
;
Li, Jia
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/02/19
obesity
inflammation
adipose tissue macrophages
adipose tissue homeostasis
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids
期刊论文
OAI收割
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2023, 卷号: 185, 页码: 13-25
作者:
Zhao, Chengcheng
;
Jiang, Xiangrui
;
Peng, Liyuan
;
Zhang, Yan
;
Li, Huihui
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/01/16
Heart failure
Hypertrophy
Epoxyeicosatrienoic acids
Soluble epoxide hydrolase
Clinically Translatable Solid-State Dye for NIR-II Imaging of Medical Devices
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 13
作者:
Li, Deling
;
Shi, Hui
;
Qi, Qingrong
;
Chang, Baisong
;
Jiang, Yuanwen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/19
aggregates
in vivo imaging
medical devices
NIR-II fluorescence
ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 46, 页码: 25283-25292
作者:
Jiang, Lulu
;
Liu, Sixiu
;
Jia, Xinglong
;
Gong, Qinting
;
Wen, Xin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/16
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
Diterpenoids from Euphorbia lactea and their anti-HIV-1 activity
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 213, 页码: 11
作者:
Zhao, Ye
;
Hua, Chen
;
Sha, Yi-ou
;
Wu, Pei-Qian
;
Liu, Qun-Fang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Euphorbia lactea Haw
Euphorbiaceae
Diterpenoid
Ingol
Ent -pimarane
Anti-HIV-1