中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2023 [1]
2021 [2]
2018 [1]
2017 [2]
2014 [1]
2010 [3]
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专题:上海药物研究所
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DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Wu, Chun-mei
;
Mao, Jia-wen
;
Zhu, Jin-zhi
;
Xie, Can-can
;
Yao, Jia-ying
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
dry eye disease
DZ2002
corneal angiogenesis
immunomodulatory function
NF-kappa B
ophthalmic therapy
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
;
Wan, Wei
;
Zhang, Yuanyuan
;
Zhang, Bidong
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Pretreatment with broad-spectrum antibiotics alters the pharmacokinetics of major constituents of Shaoyao-Gancao decoction in rats after oral administration
期刊论文
OAI收割
Acta pharmacologica Sinica, 2018
作者:
Liu, Meng
;
Yuan, Jie
;
Hu, Wen-Juan
;
Ke, Chang-Qiang
;
Zhang, Yi-Fan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270
作者:
Zhang, Wei-yao
;
Lu, Wen-chao
;
Jiang, Hao
;
Lv, Zheng-bing
;
Xie, Yi-qian
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
epigenetics
molecular docking
PRMT1
scaffold hopping
small-molecule inhibitor
New monoterpenoid oxindole alkaloid derivatives from the stems of Uncaria hirsuta Havil. and their cytotoxicity and tandem mass spectrometric fragmentation
期刊论文
OAI收割
FITOTERAPIA, 2017, 卷号: 116, 页码: 85-92
作者:
Pan, Hui-qin
;
Yang, Wen-zhi
;
Zhao, Dan
;
Luo, Cheng
;
Yao, Chang-liang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Uncaria hirsuta
Monoterpenoid oxindole alkaloid
MDA-MB-231
Collision-induced dissociation
New triterpenic acids from Uncaria rhynchophylla: Chemistry, NO-inhibitory activity, and tandem mass spectrometric analysis
期刊论文
OAI收割
FITOTERAPIA, 2014, 卷号: 96, 页码: 39-47
作者:
Zhang, Yi-bei
;
Yang, Wen-zhi
;
Yao, Chang-liang
;
Feng, Rui-hong
;
Yang, Min
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Uncaria rhynchophylla
Uncarinic acid
NO-inhibitory effect
Tandem mass spectrometric fragmentation
Unique Structural Characteristics of the Rabbit Prion Protein
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 卷号: 285, 期号: 41, 页码: 31682-31693
作者:
Wen, Yi
;
Li, Jun
;
Yao, Wenming
;
Xiong, Minqian
;
Hong, Jing
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Solution Structure and Dynamics of the I214V Mutant of the Rabbit Prion Protein
期刊论文
OAI收割
PLOS ONE, 2010, 卷号: 5, 期号: 10
作者:
Wen, Yi
;
Li, Jun
;
Xiong, Minqian
;
Peng, Yu
;
Yao, Wenming
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Characterization and Online Detection of Surfactin Isomers Based on HPLC-MSn Analyses and Their Inhibitory Effects on the Overproduction of Nitric Oxide and the Release of TNF-alpha and IL-6 in LPS-Induced Macrophages
期刊论文
OAI收割
MARINE DRUGS, 2010, 卷号: 8, 期号: 10, 页码: 2605-2618
作者:
Tang, Jin-Shan
;
Zhao, Feng
;
Gao, Hao
;
Dai, Yi
;
Yao, Zhi-Hong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
LC-MS
Bacillus sp.
surfactin isomer
anti-inflammatory activity