机构

• 上海药物研究所 [317]

采集方式

• OAI收割 [317]

内容类型

• 期刊论文 [314]
• 会议论文 [3]

发表日期

• 2024 [4]
• 2023 [30]
• 2022 [32]
• 2021 [33]
• 2020 [17]
• 2019 [27]
• 更多

学科主题

• Chemistry [3]
• Oncology [2]
• Pharmacolo... [2]
• Life Scien... [1]

筛选

浏览/检索结果: 共317条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 The development of logic gate-based fluorescent probes that respond to intracellular hydrogen peroxide and pH in tandem 期刊论文  OAI收割 TALANTA, 2024, 卷号: 270, 页码: 8 作者:  Han, Hai-Hao;  Liu, Meng-Jiao;  Zhang, Weijian;  Sun, Lu-Lu;  Ma, Xiuhua   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/19 Reactive oxygen species (ROS)  pH  Logic gate  Fluorescent probe  Cell imaging   ASAP-MS combined with mass spectrum similarity and binary code for rapid and intelligent authentication of 78 edible flowers 期刊论文  OAI收割 FOOD CHEMISTRY, 2024, 卷号: 436, 页码: 10 作者:  Meng, Qian;  Zhang, Jianqing;  Li, Xiaolan;  Li, Yun;  Shen, Xuanjing   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/19 ASAP  Flowers  MATLAB  Authentication   DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser56 to diminish pancreatic β cell function upon overnutrition 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16 作者:  Lu, Yuting;  Xu, Junyu;  Li, Yufeng;  Wang, Ruoran;  Dai, Chengqiu   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/13 Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation 期刊论文  OAI收割 CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+ 作者:  Xiao, Yufeng;  Hale, Seth;  Awasthee, Nikee;  Meng, Chengcheng;  Zhang, Xuan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/01/16 Glutamine Production by Glul Promotes Thermogenic Adipocyte Differentiation Through Prdm9-Mediated H3K4me3 and Transcriptional Reprogramming 期刊论文  OAI收割 DIABETES, 2023, 卷号: 72, 期号: 11, 页码: 24 作者:  Pan, Xiaowen;  Ye, Lingxia;  Guo, Xiaozhen;  Wang, Weihua;  Zhang, Ziyin   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/03/25 Development of PI3Kγ selective inhibitors: the strategies and application 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 10 作者:  Gu, Dong-Yan;  Zhang, Meng-Meng;  Li, Jia;  Zhou, Yu-Bo;  Sheng, Rong   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/08 PI3K  PI3K gamma inhibitors  isoform selectivity  drug development  rational drug design   Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons 期刊论文  OAI收割 MOLECULAR PSYCHIATRY, 2023, 页码: 11 作者:  Zhang, Yong-mei;  Zong, Hai-chao;  Qi, Ying-bei;  Chang, Liu-liu;  Gao, Ya-nan   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08 Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15 作者:     |  收藏  |  浏览/下载：89/0  |  提交时间：2023/10/17 Inflammatory bowel disease  Quercetin  colon-targeted delivery  Pectin microsphere  Oligochitosan  Immune microenvironment