中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [113]
采集方式
OAI收割 [113]
内容类型
期刊论文 [111]
会议论文 [2]
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2023 [11]
2022 [9]
2021 [6]
2020 [4]
2019 [2]
2018 [4]
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浏览/检索结果:
共113条,第1-10条
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专题:上海药物研究所
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MATLAB language assisted data acquisition and processing in liquid chromatography Orbitrap mass spectrometry: Application to the identification and differentiation of Radix Bupleuri from its adulterants
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2024, 卷号: 1714, 页码: 10
作者:
Shen, Xuan-jing
;
Zhang, Jian-qing
;
An, Ya-ling
;
Yang, Lin
;
Li, Xiao-lan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
Radix Bupleuri
Adulterants
MATLAB
precursor ion list (PIL)
identification
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
CD47 and PD-L1 overexpression in proliferating human hepatocytes attenuated immune responses and ameliorated acute liver injury in mice
期刊论文
OAI收割
AMERICAN JOURNAL OF TRANSPLANTATION, 2023, 卷号: 23, 期号: 12, 页码: 1832-1844
作者:
Ma, Chen
;
Cao, Huiying
;
Sun, Zhen
;
Deng, Qiangqiang
;
Liu, Wenjing
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
hepatocyte transplantation
macrophages
T cells
survival
function
The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 12
作者:
Zhou, Jiashen
;
Zhang, Lin
;
Wang, Yiran
;
Song, Wenyan
;
Huang, Yuzhou
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/08
Acyl-ACP Reductases
Allosteric Regulation
Biosynthesis
Enantioselective Reduction
Enzyme Catalysis
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:
Yang, Hanxi
;
You, Mengyuan
;
Shu, Xiaoyang
;
Zhen, Jingyao
;
Zhu, Mengwei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Peptidomimetics
Benzothiazolyl ketone
3CLpro inhibitor
Pharmacokinetic properties
SARS-CoV-2
Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial
期刊论文
OAI收割
LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13
作者:
Wang, Fuxiang
;
Xiao, Wen
;
Tang, Yimin
;
Cao, Mengli
;
Shu, Dan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Covid-19
3CL protease inhibitor
SARS-CoV-2 viral load
Alleviation of COVID-19 symptoms
Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2023, 卷号: 15, 期号: 706, 页码: 15
作者:
Ji, Shuyi
;
Feng, Li
;
Fu, Zile
;
Wu, Gaohua
;
Wu, Yingcheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Online Alkaline-pH Reverse Phase Nanoelectrospray-Tandem Mass Spectrometry Complements Conventional Low-pH Method for Global Proteomic Analysis
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2023, 卷号: 22, 期号: 5, 页码: 1446-1454
作者:
Gao, Jing
;
Wang, Yuqiu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
online alkaline-pH reverse phase
mass spectrometry
proteomics
amino acid variant
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma
期刊论文
OAI收割
NATURE METABOLISM, 2023, 页码: 35
作者:
Yang, Zijian
;
Yan, Cong
;
Ma, Jiaqiang
;
Peng, Panpan
;
Ren, Xuelian
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
Combined Use of Immune Checkpoint Inhibitors and Phytochemicals as a Novel Therapeutic Strategy against Cancer
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 12, 页码: 2315-2328
作者:
Luo, LingJie
;
Lin, Caiji
;
Wang, Pengfei
;
Cao, Danli
;
Lin, Yiru
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Immune checkpoint inhibitor
Phytochemicals
Combination therapy
Immune-related adverse events
Predictive biomarker
Gut microbiota