中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [394]
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Energy preservation for skeletal muscles: Shenqi Fuzheng injection prevents tissue wasting and restores bioenergetic profiles in a mouse model of chemotherapy-induced cachexia 期刊论文  OAI收割
PHYTOMEDICINE, 2024, 卷号: 125, 页码: 13
作者:  
Li, Wei;  Zhang, Zijia;  Berik, Entezar;  Liu, Yawen;  Pei, Wenqiang
  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/04/09
DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser56 to diminish pancreatic β cell function upon overnutrition 期刊论文  OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:  
Lu, Yuting;  Xu, Junyu;  Li, Yufeng;  Wang, Ruoran;  Dai, Chengqiu
  |  收藏  |  浏览/下载:17/0  |  提交时间:2024/03/13
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:  
Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/01/26
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:  
Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/03/25
Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2 期刊论文  OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:  
Liu, Yaowen;  Nie, Tianqing;  Hou, Jinjun;  Long, Huali;  Zhang, Zijia
  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/03/13
Comprehensive analysis of phenylpropanoids and butylidenephthalides in Angelica sinensis (Oliv.) Diels from different regions and processing methods by high-performance liquid chromatography combined with chemometrics 期刊论文  OAI收割
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2024, 页码: 16
作者:  
Sun, Yan;  Zhou, Jing;  Hu, Yuxin;  Chen, Sihan;  Ni, Hui
  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/02/27
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 3
作者:  
Yu, Lei;  Zhao, Pengcheng;  Sun, Yaoliang;  Zheng, Zening;  Du, Wenhao
  |  收藏  |  浏览/下载:1/0  |  提交时间:2024/01/26
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  
Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/12/11
Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization 期刊论文  OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 24
作者:  
Zhu, Yongcheng;  Liu, Yunyao;  Ma, Yuxiang;  Tan, Cheng;  He, Yuan
  |  收藏  |  浏览/下载:24/0  |  提交时间:2024/01/16
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:  
Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong
  |  收藏  |  浏览/下载:58/0  |  提交时间:2023/10/17